dbPTM

YAD4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YAD4_SCHPO
UniProt AC	Q09830
Protein Name	TBC domain-containing protein C4G8.04
Gene Name	SPAC4G8.04
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	772
Subcellular Localization
Protein Description
Protein Sequence	MQPSVSDSSVYLSSAPTKPIASGSVATGIDSMPSKVDITPCDLLENSKSSAPLFVECNQESLHSIPGSLHLVPDASIERLIEKHGAVNLLRQLAKDVAERDSFISDLKFHFESREYVFRELLREHGLDPVLANTKLSQRHSASFFPSSQEPSIPENPSSLTGEKPHLYARIDSAINEPFTPSDRLSPSSLVPLLKLPALDHAVSSSSSSDLPSDPNSASYIASSKQKASSLKLTSSLKKFYSWTSSSSLQHTRENLHDSTSSLRDHDPSLLSSSKFFRSSPRCSTPSVSSTFVSATSEPEVETYSVSTKNSSSNKNLRSSLSKLLSTSNLNNKPLSLSSTAPSMPSIGSVELGNMIPKETQPPSMRNDWKDYLDNNSKEILDQFGFLQKRPSHDTPLCPEDIKLNQKQTLSFYESNYGLVDDFFGNELDGLNDSPLLLNKKDILLDMKESTRQKNWSLFFQRLYKKYKITDEDTIGLLGISSIGVKGRHGKKRWHKFRELVKNGVPLCYKAKVWLECSGAYQLHSPGYYEELLSRTDEVESASVAQIDMDINRTMAKNVFFGGKGPGIPKLRRILVAYSRHNPHIGYCQGMNVIGAFLLLLYASEEDAFYMLMSIIENVLPPKYFTPDLMTSRADQLVLKSFVKESLPEIYSHLELLGVDLDAISFHWFLSVYTDTLPTNISFRIFDMLFCDGYVCLFRVALTILKSLKQQILACNSSSAIYSFLSDLVQYSFQPDSFIKEAADRWSKLVTEKSIERKRNLAISSLNLAVNY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
180	Phosphorylation	SAINEPFTPSDRLSP HHHCCCCCCHHHCCH	32.38	25720772
182	Phosphorylation	INEPFTPSDRLSPSS HCCCCCCHHHCCHHH	32.10	25720772
186	Phosphorylation	FTPSDRLSPSSLVPL CCCHHHCCHHHHHHH	24.51	25720772
188	Phosphorylation	PSDRLSPSSLVPLLK CHHHCCHHHHHHHHH	32.69	25720772
189	Phosphorylation	SDRLSPSSLVPLLKL HHHCCHHHHHHHHHH	36.45	25720772
204	Phosphorylation	PALDHAVSSSSSSDL HCCCCCCCCCCCCCC	25.86	25720772
205	Phosphorylation	ALDHAVSSSSSSDLP CCCCCCCCCCCCCCC	27.86	25720772
207	Phosphorylation	DHAVSSSSSSDLPSD CCCCCCCCCCCCCCC	35.49	25720772
229	Phosphorylation	ASSKQKASSLKLTSS HCCHHHHHHCCCCHH	43.15	25720772
230	Phosphorylation	SSKQKASSLKLTSSL CCHHHHHHCCCCHHH	34.09	25720772
234	Phosphorylation	KASSLKLTSSLKKFY HHHHCCCCHHHHHHH	18.06	25720772
235	Phosphorylation	ASSLKLTSSLKKFYS HHHCCCCHHHHHHHH	44.07	25720772
236	Phosphorylation	SSLKLTSSLKKFYSW HHCCCCHHHHHHHHC	38.68	25720772
372	Phosphorylation	MRNDWKDYLDNNSKE CCCCHHHHHHCCHHH	16.54	25720772
377	Phosphorylation	KDYLDNNSKEILDQF HHHHHCCHHHHHHHH	37.61	25720772
392	Phosphorylation	GFLQKRPSHDTPLCP CCCCCCCCCCCCCCH	37.72	21712547
395	Phosphorylation	QKRPSHDTPLCPEDI CCCCCCCCCCCHHHC	16.85	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YAD4_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YAD4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YAD4_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
SPT4_SCHPO	spt4	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YAD4_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-395, AND MASSSPECTROMETRY.	18257517 [Abstract]