XPA_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: XPA_DROME
• UniProt AC: P28518
• Protein Name: DNA repair protein complementing XP-A cells homolog
• Gene Name: Xpac
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 296
• Subcellular Localization: Nucleus.
• Protein Description: Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region (By similarity)..
• Protein Sequence: MSAEVSTNESAPPAEKKSKLTNAQKARIERNQAKAQKLREAKLVSHPFKELASNKEGGTHPEAALSQGSSVIKVQGTKYIDSGGGFLLEQPVMPTGVGPAGLNKSGEEAPPILDDAIAIPVQYEECLECGDMFADSYLFNNFGHSVCDKCRDKDERYALITRTEAKAEYLLKDCDFDKREPKLRYISRKNPHNVRWGEMKLYLHLQIHQRALEVWGSEEELVRQHEAREDKREEGKARKYNKKMKQLRMEVRSSIYTKKTHEVHEHEFGPDTYDEEEDTYTHTCITCPYSETYEKM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
256	Phosphorylation	MEVRSSIYTKKTHEV HHHHHHHHCCCCCEE	17.91	22668510
257	Phosphorylation	EVRSSIYTKKTHEVH HHHHHHHCCCCCEEE	25.13	22668510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of XPA_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of XPA_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of XPA_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DLG1_DROME	dlg1	physical	15575970
XPA_DROME	Xpac	physical	15575970
EIF3B_DROME	eIF3-S9	physical	15575970

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.