VISL1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VISL1_HUMAN
• UniProt AC: P62760
• Protein Name: Visinin-like protein 1
• Gene Name: VSNL1
• Organism: Homo sapiens (Human).
• Sequence Length: 191
• Protein Description: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner..
• Protein Sequence: MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	N-myristoyl glycine	------MGKQNSKLA ------CCCCCCCCC	40.01	-
2	Myristoylation	------MGKQNSKLA ------CCCCCCCCC	40.01	-
7	Ubiquitination	-MGKQNSKLAPEVME -CCCCCCCCCHHHHH	57.10	30230243
18	Ubiquitination	EVMEDLVKSTEFNEH HHHHHHHHCCCCCHH	59.98	30230243
36	Ubiquitination	QWYKGFLKDCPSGRL HHHHHHHHCCCCCCC	55.83	30230243
52	Phosphorylation	LEEFQQLYVKFFPYG HHHHHHHHHHHCCCC	9.39	30622161
63	Ubiquitination	FPYGDASKFAQHAFR CCCCCHHHHHHHHHH	46.57	30230243
74	Acetylation	HAFRTFDKNGDGTID HHHHHCCCCCCCEEE	59.65	30593393
74	Ubiquitination	HAFRTFDKNGDGTID HHHHHCCCCCCCEEE	59.65	30230243
90	Ubiquitination	REFICALSITSRGSF HHHHHHHCCCCCCCH	12.80	30230243
90	Phosphorylation	REFICALSITSRGSF HHHHHHHCCCCCCCH	12.80	22210691
92	Phosphorylation	FICALSITSRGSFEQ HHHHHCCCCCCCHHH	14.70	22210691
100	Ubiquitination	SRGSFEQKLNWAFNM CCCCHHHHHHEEEEC	36.27	30230243
134	Phosphorylation	AIYKMVGTVIMMKMN HHHHHHCHHHHHCCC	8.75	21406692
146	Phosphorylation	KMNEDGLTPEQRVDK CCCCCCCCHHHHHHH	30.24	24076635
156	Phosphorylation	QRVDKIFSKMDKNKD HHHHHHHHHCCCCCC	30.46	24719451
162	Ubiquitination	FSKMDKNKDDQITLD HHHCCCCCCCCCCHH	69.31	30230243
172	Ubiquitination	QITLDEFKEAAKSDP CCCHHHHHHHHHHCC	44.38	30230243
177	Phosphorylation	EFKEAAKSDPSIVLL HHHHHHHHCCCEEEE	50.45	24076635
180	Phosphorylation	EAAKSDPSIVLLLQC HHHHHCCCEEEEEEC	30.25	25332170

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VISL1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VISL1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VISL1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DTX2_HUMAN	DTX2	physical	16189514
F131C_HUMAN	FAM131C	physical	16189514
ACTB_CHICK	ACTB	physical	8780737
DTX2_HUMAN	DTX2	physical	25416956
F131C_HUMAN	FAM131C	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.