VDAC2_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VDAC2_YEAST
• UniProt AC: P40478
• Protein Name: Mitochondrial outer membrane protein porin 2
• Gene Name: POR2
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 281
• Subcellular Localization: Mitochondrion outer membrane .
• Protein Description: Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules..
• Protein Sequence: MALRFFNDISRDVNGLFNRDFFHTNPLSLNISTTTENGVNFTLKAKQGVTEGPIQTSVEGRFYDRKEGVSLSQSWSNQNRLNTRIEFSKIAPGWKGDVNAFLTPQSIKNAKFNLSYAQKSFAARTSIDILQPKDFVGSVTLGHRGFVGGTDIAYDTAAGLCARYAMSIGYLAREYSFILSTNNRQCATASFFQNVNRYLQVGTKATLQSKTSSNMNIEFVTRYVPDSISQVKAKIADSGLTTLSYKRNLNKDISLGVGMSFNALQLTEPVHKFGWSLSFSP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
50	Phosphorylation	LKAKQGVTEGPIQTS EEECCCCCCCCEEEE	41.89	29688323
56	Phosphorylation	VTEGPIQTSVEGRFY CCCCCEEEEEECCEE	35.14	29688323
57	Phosphorylation	TEGPIQTSVEGRFYD CCCCEEEEEECCEEE	11.20	29688323
63	Phosphorylation	TSVEGRFYDRKEGVS EEEECCEEECCCCCC	17.30	29688323
103	Phosphorylation	GDVNAFLTPQSIKNA CCEEEEECHHHHHHC	16.90	28889911
111	Acetylation	PQSIKNAKFNLSYAQ HHHHHHCEECCHHHH	44.15	22865919
115	Phosphorylation	KNAKFNLSYAQKSFA HHCEECCHHHHHHHH	21.37	19779198
120	Phosphorylation	NLSYAQKSFAARTSI CCHHHHHHHHCCEEC	14.19	26447709
125	Phosphorylation	QKSFAARTSIDILQP HHHHHCCEECEECCC	25.88	26447709
126	Phosphorylation	KSFAARTSIDILQPK HHHHCCEECEECCCC	16.83	26447709

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VDAC2_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VDAC2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VDAC2_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VDAC1_YEAST	POR1	genetic	9315631
SNF1_YEAST	SNF1	physical	23104570

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.