dbPTM

VAP22_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	VAP22_ARATH
UniProt AC	B9DHD7
Protein Name	Vesicle-associated protein 2-2
Gene Name	PVA22
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	386
Subcellular Localization	Endoplasmic reticulum membrane Single-pass type IV membrane protein Cytoplasmic side.
Protein Description	May play a role in vesicle trafficking..
Protein Sequence	MNMPLLDIQPRTLQFAVDLKKQTSCVVQLTNTTHHYVAFKVKTTSPKKYCVRPNVGVVAPKSTCEFTVIMQAFKEPPPDMVCKDKFLIQSTAVSAETTDEDITASMFSKAEGKHIEENKLRVTLVPPSDSPELSPINTPKQGAVFEDSILKDRLYSQSETLAPPQYEGEIVKEPRMVGHDELKAADNAKELKTPKMATVDFVEDRYTANDLKATKDSYDSSRMAKETGFDPIRSHKDADDGRAIKATTNLDAPMKKAMDLPRDQGFTNGIAVDSEPKISKERDVVQLQKTDGQNVRGLDELKLVKDIEEMKLKVDALESKLKQADSTISKLMEERSISSQHRQSLQHELAELRTKKIVKEVHNGFPLLYVCVVAFIAYVIGHFLRT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MNMPLLDI -------CCCCCCCC	9.77	22223895
123	Phosphorylation	EENKLRVTLVPPSDS CCCCEEEEEECCCCC	18.66	23776212
128	Phosphorylation	RVTLVPPSDSPELSP EEEEECCCCCCCCCC	44.65	23776212
130	Phosphorylation	TLVPPSDSPELSPIN EEECCCCCCCCCCCC	25.31	30291188
134	Phosphorylation	PSDSPELSPINTPKQ CCCCCCCCCCCCCCC	23.28	30291188
138	Phosphorylation	PELSPINTPKQGAVF CCCCCCCCCCCCCCC	32.36	23776212
279	Phosphorylation	VDSEPKISKERDVVQ CCCCCCCCCCCCEEE	34.29	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of VAP22_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of VAP22_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of VAP22_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
CNIH1_ARATH	AT3G12180	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of VAP22_ARATH

Related Literatures of Post-Translational Modification