UDS1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UDS1_SCHPO
• UniProt AC: Q9P6S3
• Protein Name: Up-regulated during septation protein 1
• Gene Name: uds1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 1052
• Subcellular Localization: Cytoplasm . Cell tip . Cell septum .
• Protein Description: Involved in septation..
• Protein Sequence: MGFHGCLSTDEYEPELIEKYGNPEPPSSSILINTRPVNPFLSTFVYVGKASSSEDVSISTGEEEMRTLLVASAVKDAKGWVYLSGKDVEEIKQKIKNLQGLLGVSIKKLAVEAKIREAAKNLMVAQAKEKKGKHKQSTIEHYEQCSRRVRELSSKIWLIERKLAEFYMHLLKHMVAVCIAELKPGSCSKVSSPVSAITADESATGFRDEEIMNNEEIEQLVERMSRILEIAQSMGNSIREPSVLDAVQMNAGERLLEQVRHLELILKQIYEKKLEEDADAKDIAPRAIVNFWRLLTELFRGDNDTPEKSNALPDDELDKHLKSDFDIESFCFLLHHLLSLYQTQKKELASSNELLASVRDENTKKLKELQDIIEEQSKHMARLHREGFSEAAENNDKPKETMPCTYDSSLADDHSDTSNLSKDKANTLCAQCSVYLSEKYQQQQSLLQLESNIQQLENEKKAAKLIEKDLLSQISHVKLQFEQQIKAHHYAKDQVRNLNDEMVALRAELEVVKAMNSQPDDPDSDYAIKQNNALQNRLEALTRENELLQSRVTTLEMEKEVQEKNSATVSNLTLKQLQMENIFASLNLENSFDFGMPLMGPYTQQNLQLEDEISEISSPSYSSDDDRKTISETQPAPKQNINEEFENSTSTDGSETNKNEQGNSLSTPDNEPRLRKESLSSDVLLDGSEKPAQAELTINSENFPVDCSLPVQTGADVVVPDTTDEEVITSEPVKLEQPINENSNVEEAEKDYQPSEKDDKSLIGGILSTVEMTQSTDVNDEIENTLTIPVEVEHSDNIDKGSEENDLGKEAVDEANNNQNDVLESVVVEQSTTTDDCENKVYEGQMNDKNSSLDMVNACEGINQTAIGFVEKPDKVTELIDEAEENIDISQDISMTETNAVDDEVQAENSILQDEVEETRQDDIEKDELEDIKEVKEDENLTTLEETIEIPANDIEVQDPEQCSCMNSTENDNITTENSSEIVQVIHTEDDSLHFDDNVSTDSVSLGNKSRISMDSMRNDCEAFLPKKEKFGSLRTLHSFESSMRRVSTSAA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Phosphorylation	FVYVGKASSSEDVSI EEEEECCCCCCCCCC		28889911
52	Phosphorylation	VYVGKASSSEDVSIS EEEECCCCCCCCCCC		28889911
53	Phosphorylation	YVGKASSSEDVSIST EEECCCCCCCCCCCC		28889911
57	Phosphorylation	ASSSEDVSISTGEEE CCCCCCCCCCCCHHH		28889911
59	Phosphorylation	SSEDVSISTGEEEMR CCCCCCCCCCHHHHH		28889911
60	Phosphorylation	SEDVSISTGEEEMRT CCCCCCCCCHHHHHH		28889911
242	Phosphorylation	GNSIREPSVLDAVQM CCCCCCCHHHHHHHC		29996109
570	Phosphorylation	EKNSATVSNLTLKQL HHHHCCHHCCCHHHH		29996109
573	Phosphorylation	SATVSNLTLKQLQME HCCHHCCCHHHHHHH		24763107
666	Phosphorylation	NEQGNSLSTPDNEPR CCCCCCCCCCCCCCC		21712547
678	Phosphorylation	EPRLRKESLSSDVLL CCCCCHHHCCCCEEC		27738172
680	Phosphorylation	RLRKESLSSDVLLDG CCCHHHCCCCEECCC		21712547
681	Phosphorylation	LRKESLSSDVLLDGS CCHHHCCCCEECCCC		21712547
755	Phosphorylation	AEKDYQPSEKDDKSL HHHHCCCCHHCCCHH		21712547
1010	Phosphorylation	SVSLGNKSRISMDSM CEECCCCCCCCHHHH		29996109
1013	Phosphorylation	LGNKSRISMDSMRND CCCCCCCCHHHHHCC		29996109
1016	Phosphorylation	KSRISMDSMRNDCEA CCCCCHHHHHCCHHH		29996109
1033	Phosphorylation	PKKEKFGSLRTLHSF CCHHHCCCCHHHHHH		25720772
1036	Phosphorylation	EKFGSLRTLHSFESS HHCCCCHHHHHHHHH		25720772
1039	Phosphorylation	GSLRTLHSFESSMRR CCCHHHHHHHHHHHH		25720772
1042	Phosphorylation	RTLHSFESSMRRVST HHHHHHHHHHHHHHC		25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UDS1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UDS1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UDS1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HPC2_SCHPO	hip4	genetic	18818364
PDP2_SCHPO	SPBC215.07c	genetic	22681890
FEN1_SCHPO	rad2	genetic	22681890
PLB2_SCHPO	SPAC1A6.03c	genetic	22681890
SET1_SCHPO	set1	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.