UB2G2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UB2G2_MOUSE
• UniProt AC: P60605
• Protein Name: Ubiquitin-conjugating enzyme E2 G2
• Gene Name: Ube2g2
• Organism: Mus musculus (Mouse).
• Sequence Length: 165
• Protein Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD)..
• Protein Sequence: MAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSMLAEPNDESGANVDASKMWRDDREQFYKIAKQIVQKSLGL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAGTALKRL ------CCHHHHHHH	24.84	-
89	Glutathionylation	IYPDGRVCISILHAP CCCCCCEEEEEEECC	1.62	24333276
106	Phosphorylation	DPMGYESSAERWSPV CCCCCCCCCCCCCCC	23.39	-
153	Ubiquitination	DDREQFYKIAKQIVQ HHHHHHHHHHHHHHH	37.16	-
156	Ubiquitination	EQFYKIAKQIVQKSL HHHHHHHHHHHHHHH	43.99	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UB2G2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UB2G2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UB2G2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
AMFR_HUMAN	AMFR	physical	11724934
HRD1_YEAST	HRD1	physical	11724934
UB2G2_MOUSE	Ube2g2	physical	17310145

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.