TTMP_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TTMP_HUMAN
• UniProt AC: Q5BVD1
• Protein Name: TPA-induced transmembrane protein
• Gene Name: TTMP
• Organism: Homo sapiens (Human).
• Sequence Length: 217
• Subcellular Localization: Endoplasmic reticulum membrane ; Single-pass type I membrane protein .
• Protein Sequence: MDLAQPSQPVDELELSVLERQPEENTPLNGADKVFPSLDEEVPPAEANKESPWSSCNKNVVGRCKLWMIITSIFLGVITVIIIGLCLAAVTYVDEDENEILELSSNKTFFIMLKIPEECVAEEELPHLLTERLTDVYSTSPSLGRYFTSVEIVDFSGENATVTYDLQFGVPSDDENFMKYMMSEELVLGILLQDFRDQNIPGCESLGLDPTSLLLYE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	Phosphorylation	ERQPEENTPLNGADK HCCCCCCCCCCCCCC	32.22	21815630
180	Phosphorylation	DDENFMKYMMSEELV CCHHHHHHHHCHHHH	6.05	-
183	Phosphorylation	NFMKYMMSEELVLGI HHHHHHHCHHHHHHH	16.05	-
190 (in isoform 3)	Phosphorylation	-	2.80	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TTMP_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TTMP_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TTMP_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SYNE4_HUMAN	SYNE4	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.