dbPTM

TSN13_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TSN13_HUMAN
UniProt AC	O95857
Protein Name	Tetraspanin-13
Gene Name	TSPAN13
Organism	Homo sapiens (Human).
Sequence Length	204
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MVCGGFACSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNQEQQGQLLEVGWNNTASARNDIQRNLNCCGFRSVNPNDTCLASCVKSDHSCSPCAPIIGEYAGEVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	S-palmitoylation	-----MVCGGFACSK -----CCCCCCCCCH	4.21	29575903
8	S-palmitoylation	MVCGGFACSKNCLCA CCCCCCCCCHHHHHH	5.78	29575903
41	Phosphorylation	GIGFGLISSLRVVGV HHCHHHHHHHHHHHH	28.50	24719451
42	Phosphorylation	IGFGLISSLRVVGVV HCHHHHHHHHHHHHH	17.13	25954137
113	N-linked_Glycosylation	QLLEVGWNNTASARN CEEEECCCCHHHHHH	30.00	UniProtKB CARBOHYD
137	N-linked_Glycosylation	GFRSVNPNDTCLASC CCCCCCCCCCEEHHH	52.61	17660510
139	Phosphorylation	RSVNPNDTCLASCVK CCCCCCCCEEHHHHC	18.96	25262027
143	Phosphorylation	PNDTCLASCVKSDHS CCCCEEHHHHCCCCC	13.39	25849741
201	Phosphorylation	KDPRANPSAFL---- CCCCCCCCCCC----	31.31	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TSN13_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TSN13_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TSN13_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TSN13_HUMAN

Related Literatures of Post-Translational Modification