TON1A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TON1A_ARATH
• UniProt AC: Q9FQ25
• Protein Name: Protein TONNEAU 1a
• Gene Name: TON1A
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 260
• Subcellular Localization: Cytoplasm . Cytoplasm, cytoskeleton . Localizes to cytoplasm and cortical cytoskeletal structures, including the preprophase band and the interphase microtubule arrays (PubMed:18757558). Recruited to cytoskeletal structures by LNG2/TRM1 (PubMed:22286
• Protein Description: Involved in the control of the dynamic organization of the cortical cytoskeleton. May play a role in the organization of microtubule arrays at the centrosome through interaction with centrin 1 (CEN1)..
• Protein Sequence: MDDYTREMMDLKTLVTRTLEKKGVLAKIRAELRASVFEAIEEEDRVIENNEGPPPALLGSCNDRARKLHASPSGRLLSALICEYLDWAQLNHTLIVYQPESNLPKDSWKSELRDFNSNNGFELNRNGDSGPLLLDVLEGFLKFESMTQGMGSSSRRDSETESSSSLESRNPPRRSSASDSLPPQRRPVSASQASDRRAGLSTSGYRKDEFNWRQGNQDTHEEVTRASAALENLQLDRKTRNLTSSWRNVRDGTNEEEGRD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
145	Phosphorylation	EGFLKFESMTQGMGS HHHHHHHHHHCCCCC		25561503
147	Phosphorylation	FLKFESMTQGMGSSS HHHHHHHHCCCCCCC		25561503
152	Phosphorylation	SMTQGMGSSSRRDSE HHHCCCCCCCCCCCC		23172892
153	Phosphorylation	MTQGMGSSSRRDSET HHCCCCCCCCCCCCC		17317660
154	Phosphorylation	TQGMGSSSRRDSETE HCCCCCCCCCCCCCC		30407730
158	Phosphorylation	GSSSRRDSETESSSS CCCCCCCCCCCCCCC		23776212
160	Phosphorylation	SSRRDSETESSSSLE CCCCCCCCCCCCCHH		23776212
175	Phosphorylation	SRNPPRRSSASDSLP HCCCCCCCCCCCCCC		29654922
176	Phosphorylation	RNPPRRSSASDSLPP CCCCCCCCCCCCCCC		25561503
189	Phosphorylation	PPQRRPVSASQASDR CCCCCCCCHHHHHHH		29654922
245	Phosphorylation	KTRNLTSSWRNVRDG HHCCCCHHHCCCCCC		19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TON1A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TON1A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TON1A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LNG2_ARATH	LNG2	physical	22286137
CE350_HUMAN	CEP350	physical	22286137

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.