TMM54_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TMM54_HUMAN
• UniProt AC: Q969K7
• Protein Name: Transmembrane protein 54
• Gene Name: TMEM54
• Organism: Homo sapiens (Human).
• Sequence Length: 222
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MCLRLGGLSVGDFRKVLMKTGLVLVVLGHVSFITAALFHGTVLRYVGTPQDAVALQYCVVNILSVTSAIVVITSGIAAIVLSRYLPSTPLRWTVFSSSVACALLSLTCALGLLASIAMTFATQGKALLAACTFGSSELLALAPDCPFDPTRIYSSSLCLWGIALVLCVAENVFAVRCAQLTHQLLELRPWWGKSSHHMMRENPELVEGRDLLSCTSSEPLTL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	CLRLGGLSVGDFRKV CCCCCCCCHHHHHHH	27.59	22985185
20	Phosphorylation	FRKVLMKTGLVLVVL HHHHHHHCCCEEEEC	23.06	-
41	Phosphorylation	TAALFHGTVLRYVGT HHHHHCCHHHHHCCC	14.06	-
87	Phosphorylation	VLSRYLPSTPLRWTV HHHHHCCCCCCCHHH	39.81	24719451
221	Phosphorylation	CTSSEPLTL------ CCCCCCCCC------	40.93	28348404

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TMM54_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TMM54_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TMM54_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CDK2_HUMAN	CDK2	physical	19829063
RARA_HUMAN	RARA	physical	22982681

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.