TMA7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TMA7_HUMAN
• UniProt AC: Q9Y2S6
• Protein Name: Translation machinery-associated protein 7
• Gene Name: TMA7
• Organism: Homo sapiens (Human).
• Sequence Length: 64
• Protein Sequence: MSGREGGKKKPLKQPKKQAKEMDEEDKAFKQKQKEEQKKLEELKAKAAGKGPLATGGIKKSGKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSGREGGKK ------CCCCCCCCC		-
16	Acetylation	KKPLKQPKKQAKEMD CCCCCCCHHHHHHCH		30584205
17	Acetylation	KPLKQPKKQAKEMDE CCCCCCHHHHHHCHH		26051181
20	Acetylation	KQPKKQAKEMDEEDK CCCHHHHHHCHHHHH		26051181
22	Sulfoxidation	PKKQAKEMDEEDKAF CHHHHHHCHHHHHHH		21406390
27	Ubiquitination	KEMDEEDKAFKQKQK HHCHHHHHHHHHHHH		-
27	Acetylation	KEMDEEDKAFKQKQK HHCHHHHHHHHHHHH		23236377
30	Acetylation	DEEDKAFKQKQKEEQ HHHHHHHHHHHHHHH		25953088
30	Ubiquitination	DEEDKAFKQKQKEEQ HHHHHHHHHHHHHHH		-
32	Methylation	EDKAFKQKQKEEQKK HHHHHHHHHHHHHHH		-
32	Ubiquitination	EDKAFKQKQKEEQKK HHHHHHHHHHHHHHH		-
39	Ubiquitination	KQKEEQKKLEELKAK HHHHHHHHHHHHHHH		-
44	Ubiquitination	QKKLEELKAKAAGKG HHHHHHHHHHHCCCC		23000965
44	Acetylation	QKKLEELKAKAAGKG HHHHHHHHHHHCCCC		26051181
46	Methylation	KLEELKAKAAGKGPL HHHHHHHHHCCCCCC		-
46	Ubiquitination	KLEELKAKAAGKGPL HHHHHHHHHCCCCCC		23000965
50	Methylation	LKAKAAGKGPLATGG HHHHHCCCCCCCCCC		-
50	Ubiquitination	LKAKAAGKGPLATGG HHHHHCCCCCCCCCC		23000965
50	Acetylation	LKAKAAGKGPLATGG HHHHHCCCCCCCCCC		25953088
55	Phosphorylation	AGKGPLATGGIKKSG CCCCCCCCCCCCCCC		27470641
59	Acetylation	PLATGGIKKSGKK-- CCCCCCCCCCCCC--		25953088
59	Ubiquitination	PLATGGIKKSGKK-- CCCCCCCCCCCCC--		33845483
61	Phosphorylation	ATGGIKKSGKK---- CCCCCCCCCCC----		26074081
61	ADP-ribosylation	ATGGIKKSGKK---- CCCCCCCCCCC----		28190768
63	Acetylation	GGIKKSGKK------ CCCCCCCCC------		130263

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TMA7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TMA7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TMA7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
NF2IP_HUMAN	NFATC2IP	physical	26344197

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.