| UniProt ID | TM139_HUMAN | |
|---|---|---|
| UniProt AC | Q8IV31 | |
| Protein Name | Transmembrane protein 139 | |
| Gene Name | TMEM139 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 216 | |
| Subcellular Localization |
Membrane Single-pass type I membrane protein . |
|
| Protein Description | May be involved in cellular trafficking of proteins such as SLC4A1.. | |
| Protein Sequence | MVPMHLLGRLEKPLLLLCCASFLLGLALLGIKTDITPVAYFFLTLGGFFLFAYLLVRFLEWGLRSQLQSMQTESPGPSGNARDNEAFEVPVYEEAVVGLESQCRPQELDQPPPYSTVVIPPAPEEEQPSHPEGSRRAKLEQRRMASEGSMAQEGSPGRAPINLRLRGPRAVSTAPDLQSLAAVPTLEPLTPPPAYDVCFGHPDDDSVFYEDNWAPP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 146 | Phosphorylation | LEQRRMASEGSMAQE HHHHHHHHCCCCCCC | 32.90 | 21815630 | |
| 149 | Phosphorylation | RRMASEGSMAQEGSP HHHHHCCCCCCCCCC | 13.59 | 30242111 | |
| 155 | Phosphorylation | GSMAQEGSPGRAPIN CCCCCCCCCCCCCEE | 24.35 | 28102081 | |
| 172 | Phosphorylation | LRGPRAVSTAPDLQS ECCCCCCCCCCCHHH | 20.19 | 28348404 | |
| 173 | Phosphorylation | RGPRAVSTAPDLQSL CCCCCCCCCCCHHHH | 35.29 | 28348404 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TM139_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TM139_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TM139_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| TRI68_HUMAN | TRIM68 | physical | 26186194 | |
| KS6A3_HUMAN | RPS6KA3 | physical | 26186194 | |
| KS6A3_HUMAN | RPS6KA3 | physical | 28514442 | |
| TRI68_HUMAN | TRIM68 | physical | 28514442 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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