TIP22_ARATH - dbPTM
TIP22_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TIP22_ARATH
UniProt AC Q41975
Protein Name Probable aquaporin TIP2-2
Gene Name TIP2-2
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 250
Subcellular Localization Vacuole membrane
Multi-pass membrane protein . Tonoplast.
Protein Description Aquaporins facilitate the transport of water and small neutral solutes across cell membranes..
Protein Sequence MVKIEIGSVGDSFSVASLKAYLSEFIATLLFVFAGVGSALAFAKLTSDAALDPAGLVAVAVAHAFALFVGVSIAANISGGHLNPAVTLGLAVGGNITVITGFFYWIAQCLGSIVACLLLVFVTNGESVPTHGVAAGLGAIEGVVMEIVVTFALVYTVYATAADPKKGSLGTIAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVVSGDFSQIWIYWVGPLVGGALAGLIYGDVFIGSYAPAPTTESYP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
1Acetylation-------MVKIEIGS
-------CEEEEECC
6.63-
3"N6,N6-dimethyllysine"-----MVKIEIGSVG
-----CEEEEECCCC
33.07-
3Methylation-----MVKIEIGSVG
-----CEEEEECCCC
33.07-
248PhosphorylationAPAPTTESYP-----
CCCCCCCCCC-----
40.38-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TIP22_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TIP22_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TIP22_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
Y4645_ARATHAT4G26450physical
21798944
NAC89_ARATHNAC089physical
21798944
NIP11_ARATHNLM1physical
21798944
GONS1_ARATHGONST1physical
22737156
UPS1_ARATHUPS1physical
22737156
TIP13_ARATHTIP1;3physical
24833385

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TIP22_ARATH

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Related Literatures of Post-Translational Modification

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