TIGD7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TIGD7_HUMAN
• UniProt AC: Q6NT04
• Protein Name: Tigger transposable element-derived protein 7
• Gene Name: TIGD7
• Organism: Homo sapiens (Human).
• Sequence Length: 549
• Subcellular Localization: Nucleus .
• Protein Sequence: MNKRGKYTTLNLEEKMKVLSRIEAGRSLKSVMDEFGISKSTFYDIKKNKKLILDFVLKQDMPLVGAEKRKRTTGAKYGDVDDAVYMWYQQKRSAGVPVRGVELQAAAERFARCFGRTDFKASTGWLFRFRNRHAIGNRKGCGEQVLSSVSENVEPFRQKLSMIIKEEKLCLAQLYSGDETDLFWKSMPENSQASRKDICLPGKKINKERLSAFLCANADGTHKLKSIIIGKSKLPKSVKEDTSTLPVIYKPSKDVWFTRELFSEWFFQNFVPEVRHFQLNVLRFHDEDVRALLLLDSCPAHPSSESLTSEDGRIKCMFFPHNTSTLIQPMNQGVILSCKRLYRWKQLEESLVIFEESDDEQEKGDKGVSKIKIYNIKSAIFNWAKSWEEVKQITIANAWENLLYKKEPEYDFQGLEHGDYREILEKCGELETKLDDDRVWLNGDEEKGCLLKTKGGITKEVVQKGGEAEKQTAEFKLSAVRESLDYLLDFVDATPEFQRFHFTLKEMQQEIVKKQFQSKIHSRIGSFLKPRPHNIKDSFSGPSTSGSNH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Methylation	TTLNLEEKMKVLSRI CCCCHHHHHHHHHHH	34.35	-
85	Phosphorylation	GDVDDAVYMWYQQKR CCHHHHHHHHHHHHC	5.44	-
88	Phosphorylation	DDAVYMWYQQKRSAG HHHHHHHHHHHCCCC	5.64	-
223	Ubiquitination	ANADGTHKLKSIIIG CCCCCCCCCEEEEEC	58.40	30230243
242	Phosphorylation	PKSVKEDTSTLPVIY CCCCCCCCCCCCEEE	25.38	25072903
243	Phosphorylation	KSVKEDTSTLPVIYK CCCCCCCCCCCEEEC	40.02	25072903
244	Phosphorylation	SVKEDTSTLPVIYKP CCCCCCCCCCEEECC	36.85	25072903
249	Phosphorylation	TSTLPVIYKPSKDVW CCCCCEEECCCCCEE	19.65	25072903
252	Phosphorylation	LPVIYKPSKDVWFTR CCEEECCCCCEEEEH	37.02	25072903
323	Phosphorylation	CMFFPHNTSTLIQPM EEEECCCCCCCCCCC	21.76	-
324	Phosphorylation	MFFPHNTSTLIQPMN EEECCCCCCCCCCCC	26.91	-
337	Phosphorylation	MNQGVILSCKRLYRW CCCCEEEEEEEHHHH	13.38	-
357	Phosphorylation	SLVIFEESDDEQEKG HEEEEECCCCCCCCC	43.07	27251275
526	Phosphorylation	KIHSRIGSFLKPRPH HHHHHCHHHCCCCCC	25.65	24719451
544	Phosphorylation	DSFSGPSTSGSNH-- CCCCCCCCCCCCC--	39.99	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TIGD7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TIGD7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TIGD7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UACA_HUMAN	UACA	physical	26186194
UACA_HUMAN	UACA	physical	28514442
F16P1_HUMAN	FBP1	physical	28514442
ANM8_HUMAN	PRMT8	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.