THAP6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: THAP6_HUMAN
• UniProt AC: Q8TBB0
• Protein Name: THAP domain-containing protein 6
• Gene Name: THAP6
• Organism: Homo sapiens (Human).
• Sequence Length: 222
• Protein Sequence: MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDVLCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNHHLVGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQKSLRKTIRELKDECLISQETANRLDTFCWDCCQESIEQDYIS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Acetylation	TDENIKRKWVLAMKR CCHHHHHHHHHEEEE	36.33	11504383
56	Acetylation	AAGIWEPKKGDVLCS CCCCCCCCCCCEEEE	58.85	11504391
166	Ubiquitination	IGELEDTKESLRNVL HHCHHHHHHHHHHHH	58.59	-
191	Ubiquitination	RKTIRELKDECLISQ HHHHHHHHHHHCCCH	46.88	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of THAP6_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of THAP6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of THAP6_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KR107_HUMAN	KRTAP10-7	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.