TEKT5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TEKT5_HUMAN
• UniProt AC: Q96M29
• Protein Name: Tektin-5
• Gene Name: TEKT5
• Organism: Homo sapiens (Human).
• Sequence Length: 485
• Subcellular Localization: Cell projection, cilium, flagellum . Appears to be associated with flagellar accessory structures and not the axoneme.
• Protein Description: May be a structural component of the sperm flagellum..
• Protein Sequence: MEFLGTTQTASYCGPKKCCGLTSLPAVQAPVIQECYQPYYLPGYRYLNSWRPSLFYKIANVQTCPDESTSTLRPPTILPTLRSALFSRYSPHDWDQSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGMRKTFPCTPRLVGHT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MEFLGTTQTASYC --CCCCCCCCCCCCC	20.20	24043423
7	Phosphorylation	-MEFLGTTQTASYCG -CCCCCCCCCCCCCC	23.32	24043423
9	Phosphorylation	EFLGTTQTASYCGPK CCCCCCCCCCCCCCC	18.58	24043423
11	Phosphorylation	LGTTQTASYCGPKKC CCCCCCCCCCCCCCC	25.09	24043423
12	Phosphorylation	GTTQTASYCGPKKCC CCCCCCCCCCCCCCC	10.04	24043423
63	Phosphorylation	YKIANVQTCPDESTS HHEECCEECCCCCCC	23.02	22817900
68	Phosphorylation	VQTCPDESTSTLRPP CEECCCCCCCCCCCC	34.73	30622161
69	Phosphorylation	QTCPDESTSTLRPPT EECCCCCCCCCCCCC	24.55	22817900
70	Phosphorylation	TCPDESTSTLRPPTI ECCCCCCCCCCCCCH	34.42	30622161
71	Phosphorylation	CPDESTSTLRPPTIL CCCCCCCCCCCCCHH	27.20	22817900
76	Phosphorylation	TSTLRPPTILPTLRS CCCCCCCCHHHHHHH	37.52	25693802
80	Phosphorylation	RPPTILPTLRSALFS CCCCHHHHHHHHHHH	31.21	25693802
90	Phosphorylation	SALFSRYSPHDWDQS HHHHHCCCCCCCCCC	18.04	25693802
146	Phosphorylation	RNLGQRLSDIGFWKS CHHHHHHHHHCCCHH	29.39	25693802
222	Acetylation	IREVDLLKCCQEQMR HHHHHHHHHHHHHHH	40.02	25038526
265	Acetylation	SAQCIDEKCFNLRNT HHHHHCHHHHCCCCH	40.14	25038526
306	O-linked_Glycosylation	SNDNIKHSQNMRANS CCCCCCCCCHHHHCH	20.46	30379171
353	Acetylation	ISEVTDVKNKLQTQL HHHHHHHHHHHHHHH	51.69	23236377
447	Acetylation	LQLLVMTKCRLEHEL HHHHHHHHCCHHHHH	10.16	25038526
465	Acetylation	ANTLCIDKEKCMGMR CCEEEECHHHHCCCC	38.88	25038526
467	Acetylation	TLCIDKEKCMGMRKT EEEECHHHHCCCCCC	34.95	25038526
474	O-linked_Glycosylation	KCMGMRKTFPCTPRL HHCCCCCCCCCCHHC	23.57	30379171

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TEKT5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TEKT5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TEKT5_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KLH38_HUMAN	KLHL38	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.