TCPE_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TCPE_CAEEL
• UniProt AC: P47209
• Protein Name: T-complex protein 1 subunit epsilon
• Gene Name: cct-5
• Organism: Caenorhabditis elegans.
• Sequence Length: 542
• Subcellular Localization: Cytoplasm.
• Protein Description: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin..
• Protein Sequence: MAQSSAQLLFDESGQPFIVMREQENQKRITGVEAVKSHILAARAVANTLRTSLGPRGLDKMLVSPDGDVTITNDGATIMEKMDVQHHVAKLMVELSKSQDHEIGDGTTGVVVLAGALLEEAEKLIDRGIHPIKIADGFDLACKKALETLDSISDKFPVENRERLVETAQTSLGSKIVNRSLRQFAEIAVDAVLSVADIESKDVNFEMIKMEGKVGGRLEDTILVKGIVIDKTMSHPQMPKELKNAKVAILTCPFEPPKPKTKHKLDITSTEDFKALRDYERETFETMIRQVKESGATLAICQWGFDDEANHLLQANDLPAVRWVGGPEIELLAIATNARIVPRFSELSKEKLGTAGLVREITFGAAKDRMLSIEQCPNNKAVTIFVRGGNKMIIDEAKRALHDALCVIRNLVRDSRIVYGGGSAELAAAIQVAKEADRIDGIEQYAFRAFADALESIPMALAENSGLAPIDALSDLKAKQIETGKSSLGIDAVFAGTNDMKEQKVIETLLSKREQISLATQVVRMILKIDDVRVPDDERMGY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MAQSSAQLLFD ----CCCCCCHHHHC	20.36	28854356
5	Phosphorylation	---MAQSSAQLLFDE ---CCCCCCHHHHCC	14.14	28854356
30	Phosphorylation	QENQKRITGVEAVKS HHHCCCCCHHHHHHH	38.93	28854356
64	Phosphorylation	GLDKMLVSPDGDVTI CCCCEEECCCCCEEE	17.20	28854356
268	Phosphorylation	TKHKLDITSTEDFKA CCCCCCCCCHHHHHH	29.30	30078680
269	Phosphorylation	KHKLDITSTEDFKAL CCCCCCCCHHHHHHH	30.08	30078680
270	Phosphorylation	HKLDITSTEDFKALR CCCCCCCHHHHHHHH	30.81	30078680
345	Phosphorylation	ARIVPRFSELSKEKL CEECCCHHHHCHHHH	38.62	28854356

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TCPE_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TCPE_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TCPE_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YSL1_CAEEL	F13B12.4	physical	14704431

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.