dbPTM

YSL1_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YSL1_CAEEL
UniProt AC	Q19374
Protein Name	Putative pyridoxal-phosphate dependent protein F13B12.4
Gene Name	F13B12.4
Organism	Caenorhabditis elegans.
Sequence Length	435
Subcellular Localization
Protein Description
Protein Sequence	MKLLLLALFLSISASCLAEDITKISESRIPNEDAVPDYEAKWRLGAIQKLWNERRKMGHTPMTKFSPPGFPNADIFFKNETATATRTLKHRFAWALLLWAITEGKVTSKTSAVYDSTSGNTGSAEAYMCTLVNVPYYAVVADNLEKEKVKQIESFGGKIIKVPVALRNAKAKEFADKNHGFYMNQFGNAEKAEEFHESGDFYFESTNVYHEIIVQLKKDKEQIVKIPDYFVHSAGTGGTISSVGRYVARYGAPTKVVLSDSQYSLFYDYVIGHKFTNQSGAGIWTPPGIAGIGYGYDIEPVWYGETTSLTRNVIHEAMKMPDIASVATMRILDEKGYNVGPSTSLNFLVSLYKAYQNKARKSAIKHRLTIVTLACDPGDFYRSTYLNNEWVEKSFKKFGGVMGMECWKKLIQESIDTGSDFYSKGLTMCPGAFKV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
79	N-linked_Glycosylation	NADIFFKNETATATR CCCEEEECCCCCHHH	46.85	17761667
89	N6-(pyridoxal phosphate)lysine	ATATRTLKHRFAWAL CCHHHHHHHHHHHHH	31.92	-
89	Other	ATATRTLKHRFAWAL CCHHHHHHHHHHHHH	31.92	-
277	N-linked_Glycosylation	VIGHKFTNQSGAGIW ECCCCCCCCCCCCCC	36.83	17761667

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YSL1_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YSL1_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YSL1_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YSL1_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YSL1_CAEEL

Related Literatures of Post-Translational Modification

N-linked Glycosylation
Reference	PubMed
"Proteomics reveals N-linked glycoprotein diversity in Caenorhabditiselegans and suggests an atypical translocation mechanism for integralmembrane proteins."; Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,Taoka M., Takahashi N., Isobe T.; Mol. Cell. Proteomics 6:2100-2109(2007). Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-79 AND ASN-277, AND MASSSPECTROMETRY.	17761667 [Abstract]
"Lectin affinity capture, isotope-coded tagging and mass spectrometryto identify N-linked glycoproteins."; Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J.,Kasai K., Takahashi N., Isobe T.; Nat. Biotechnol. 21:667-672(2003). Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-79, AND MASS SPECTROMETRY.	12754521 [Abstract]