TCP2L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TCP2L_HUMAN
• UniProt AC: B9ZVM9
• Protein Name: T-complex protein 10A homolog 2
• Gene Name: TCP10L2
• Organism: Homo sapiens (Human).
• Sequence Length: 353
• Protein Sequence: MLEGQLEAREPKEGTHPEDPCPGAGAAMEKTPAAAEVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKTPPQEDREKSPPGRRQDRSPAPTGRPTPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQASQAATLQEQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQAMDTKMKKEEVQEEKRHPNGKADDCRRSGFPSEFPGALHAAPSRQDMGP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
202	Phosphorylation	QDRSPAPTGRPTPGA CCCCCCCCCCCCCCC	48.18	-
281	Phosphorylation	VQAEEFASSSPDSAE HHHHHHHHCCCCHHH	36.35	24114839
283	Phosphorylation	AEEFASSSPDSAERQ HHHHHHCCCCHHHHC	30.17	24114839
286	Phosphorylation	FASSSPDSAERQNLP HHHCCCCHHHHCCCC	35.10	24114839
332	Phosphorylation	KADDCRRSGFPSEFP CHHHHHHCCCCCCCC	25.98	24719451
336	Phosphorylation	CRRSGFPSEFPGALH HHHCCCCCCCCCCCC	50.00	23607784
347	Phosphorylation	GALHAAPSRQDMGP- CCCCCCCCCCCCCC-	37.54	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TCP2L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TCP2L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TCP2L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TCP10_HUMAN	TCP10	physical	26186194
TMF1_HUMAN	TMF1	physical	26186194
GRAP1_HUMAN	GRIPAP1	physical	26186194
MPRIP_HUMAN	MPRIP	physical	26186194
TCP10_HUMAN	TCP10	physical	28514442
GRAP1_HUMAN	GRIPAP1	physical	28514442
TMF1_HUMAN	TMF1	physical	28514442
MPRIP_HUMAN	MPRIP	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.