TCFL5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TCFL5_HUMAN
• UniProt AC: Q9UL49
• Protein Name: Transcription factor-like 5 protein
• Gene Name: TCFL5
• Organism: Homo sapiens (Human).
• Sequence Length: 500
• Subcellular Localization: Nucleus .
• Protein Description: Putative transcription factor. Isoform 3 may play a role in early spermatogenesis..
• Protein Sequence: MSGPGPREPPPEAGAAGGEAAVEGAGGGDAALGEPGLSFTTTDLSLVEMTEVEYTQLQHILCSHMEAAADGELETRLNSALLAAAGPGAGAGGFAAGGQGGAAPVYPVLCPSALAADAPCLGHIDFQELRMMLLSEAGAAEKTSGGGDGARARADGAAKEGAGAAAAAAGPDGAPEARAKPAVRVRLEDRFNSIPAEPPPAPRGPEPPEPGGALNNLVTLIRHPSELMNVPLQQQNKCTALVKNKTAATTTALQFTYPLFTTNACSTSGNSNLSQTQSSSNSCSVLEAAKHQDIGLPRAFSFCYQQEIESTKQTLGSRNKVLPEQVWIKVGEAALCKQALKRNRSRMRQLDTNVERRALGEIQNVGEGATATQGAWQSSESSQANLGEQAQSGPQGGRSQRRERHNRMERDRRRRIRICCDELNLLVPFCNAETDKATTLQWTTAFLKYIQERHGDSLKKEFESVFCGKTGRRLKLTRPDSLVTCPAQGSLQSSPSMEIK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
75	Phosphorylation	AADGELETRLNSALL HCCCCHHHHHHHHHH	53.75	-
143	Phosphorylation	EAGAAEKTSGGGDGA HCCCCHHCCCCCCHH	24.90	28060719
144	Phosphorylation	AGAAEKTSGGGDGAR CCCCHHCCCCCCHHH	46.65	28060719
225	Phosphorylation	VTLIRHPSELMNVPL HHHHCCHHHHCCCCH	36.92	-
301	Phosphorylation	IGLPRAFSFCYQQEI CCCCHHHHHHHHHHH	17.27	-
443	Phosphorylation	KATTLQWTTAFLKYI HHHHHHHHHHHHHHH	8.69	22210691
444	Phosphorylation	ATTLQWTTAFLKYIQ HHHHHHHHHHHHHHH	16.68	22210691
490	Phosphorylation	VTCPAQGSLQSSPSM EECCCCCCCCCCCCC	15.91	28348404
493	Phosphorylation	PAQGSLQSSPSMEIK CCCCCCCCCCCCCCC	49.89	25627689
494	Phosphorylation	AQGSLQSSPSMEIK- CCCCCCCCCCCCCC-	14.18	27050516

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TCFL5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TCFL5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TCFL5_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
USF1_HUMAN	USF1	physical	12923186

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.