TCF21_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TCF21_MOUSE
• UniProt AC: O35437
• Protein Name: Transcription factor 21
• Gene Name: Tcf21
• Organism: Mus musculus (Mouse).
• Sequence Length: 179
• Subcellular Localization: Nucleus .
• Protein Description: Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. May be involved in the organogenesis of the spleen and heart and in cardiac and coronary artery development. May function in the development and sex differentiation of gonad via transcriptional regulation of AD4BP/SF-1..
• Protein Sequence: MSTGSLSDVEDLQEVEMLDCDSLKVDSNKEFGTSNESTEEGSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPENDLKEVVTANRLCGTTAS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
104	Phosphorylation	KAFSRLKTTLPWVPP HHHHHHHHCCCCCCC	37.85	20139300
105	Phosphorylation	AFSRLKTTLPWVPPD HHHHHHHCCCCCCCC	29.27	20139300
116	Phosphorylation	VPPDTKLSKLDTLRL CCCCCCHHHHHHHHH	32.50	20139300

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TCF21_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TCF21_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TCF21_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ANDR_MOUSE	Ar	physical	15919722
HDAC1_MOUSE	Hdac1	physical	15919722

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.