dbPTM

TAP46_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TAP46_ARATH
UniProt AC	Q8LDQ4
Protein Name	PP2A regulatory subunit TAP46 {ECO:0000303\|PubMed:10517853}
Gene Name	TAP46 {ECO:0000303\|PubMed:10517853}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	405
Subcellular Localization
Protein Description	Involved in the positive regulation of the TOR signaling pathway. [PubMed: 21216945]
Protein Sequence	MGGLAMEEMPLSVLFEQARKIHLAASESGVDQDVVKKGCEMFQKCEDMIGKLALFSSNETKEDISTNNLKYLLVPYYLAELTEKIIQEDRIQIVKASYAKLKEFFSFCEAMELVPDEELEASSRGGSGAPADRRALKIARFKRQKAAEAKLLEIKERKERRGRSTKASALSTPVESGEDDIPDDDSEEEREAWLSSINLAICKAIDLLEMLKREEEMLSAIKERQLKDGEGGFSRDALDDRTKKAETWHRDAAARIQYSKPAQPITCATFAQDVLEGRASVSQGHEHKNQPLIFGPASIVGGPLSTERERMIAQVFQPSHRMPTMCIEDAGLTEMNIMNDWQEQTKKAIEEATTSWYNDKPLRRKEEDEEDDDEDEEAVMKARAFDDWKDDNPRGAGNKKLTPCG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
353	Phosphorylation	KKAIEEATTSWYNDK HHHHHHHHHHHHCCC	25.33	24243849
354	Phosphorylation	KAIEEATTSWYNDKP HHHHHHHHHHHCCCC	25.06	24243849
355	Phosphorylation	AIEEATTSWYNDKPL HHHHHHHHHHCCCCC	24.17	24243849

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TAP46_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TAP46_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TAP46_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PP2A2_ARATH	PP2A-2	physical	10517853
PPX1_ARATH	PPX1	physical	21216945
PP2A3_ARATH	PP2A-3	physical	21216945
ABI5_ARATH	ABI5	physical	24357600
KPK1_ARATH	PK1	physical	25399018
KPK2_ARATH	S6K2	physical	25399018

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TAP46_ARATH

Related Literatures of Post-Translational Modification