SVBP_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SVBP_HUMAN
• UniProt AC: Q8N300
• Protein Name: Small vasohibin-binding protein {ECO:0000303|PubMed:20736312}
• Gene Name: SVBP {ECO:0000303|PubMed:20736312}
• Organism: Homo sapiens (Human).
• Sequence Length: 66
• Subcellular Localization: Secreted . Detected both intracellularly and extracellularly. Within cells, localizes mainly to the apical part of the cell.
• Protein Description: Enhances the solubility and secretion of VASH1 and prevents its ubiquitination. Also enhances secretion of VASH2..
• Protein Sequence: MDPPARKEKTKVKESVSRVEKAKQKSAQQELKQRQRAEIYALNRVMTELEQQQFDEFCKQMQPPGE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Ubiquitination	RKEKTKVKESVSRVE HHHHHHHHHHHHHHH		24816145
23	Ubiquitination	VSRVEKAKQKSAQQE HHHHHHHHHHHHHHH		24816145
40	Phosphorylation	QRQRAEIYALNRVMT HHHHHHHHHHHHHHH		21945579
46	Sulfoxidation	IYALNRVMTELEQQQ HHHHHHHHHHHHHHH		21406390

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SVBP_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SVBP_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SVBP_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VASH1_HUMAN	VASH1	physical	20736312

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.