STE7_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: STE7_SCHPO
• UniProt AC: Q10136
• Protein Name: Protein ste7
• Gene Name: ste7
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 569
• Protein Description: Has a role in promoting meiosis whereby it is involved in establishing the mating pheromone signaling pathway. It also has a role in suppressing meiosis until the conjugation process is complete..
• Protein Sequence: MFLEIILDSATYSFDRVITGKICFETNAATSPRSFQIQLRIKGYAVYHHGFLSSPSHKHPTTASASDSDEATEIFTHSQPLPIPAGPSSKSHAIDFKFKFPSKSASSLPCSKSNDSMVNICYMLKATISKRYAFLGSSQSAKAELIMVPPNLAGKPLSANSSFGSSAKTFQLPEFDSVTPSASLYKQPSFNSNPAPITTSSATHTSQFSTSSSSSVNSVHTPVMVPNPYFQYNSSMTAPSSSSSSVAPFVPRRQFSVSSASDPPQTPISMSPPIPPTPSQFSAFMYQNQQSYLSPQSHYENPLSISSRPSPCCPSTPSSAVTLSNGFDSQSNAYNNSGTGPPMLYKFPQRSYTAPNTSFNSQRRMSSITSLPTASFCPVKHGVSPPSLAGNQPSPLSSPLTNSNVSPSTICSPDNNVTFVNLAPGEKLTFKIEPNDLMDEEEVVENSNMYSIPGKTVATTVCHSSSSSGDFSALSCHRNLSFSESLPTAEDQVHNNHCAVSPSRRSSSNALYLATLPMGYERSNSVSYCSDSSLSSPLPDDNMLQDPHALNMAYAKEFDVLINEVLQSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
47	Phosphorylation	RIKGYAVYHHGFLSS EECEEEEEECCCCCC	4.67	21712547
53	Phosphorylation	VYHHGFLSSPSHKHP EEECCCCCCCCCCCC	37.63	21712547
54	Phosphorylation	YHHGFLSSPSHKHPT EECCCCCCCCCCCCC	32.35	21712547
179	Phosphorylation	LPEFDSVTPSASLYK CCCCCCCCCCCHHHC	18.58	21712547
183	Phosphorylation	DSVTPSASLYKQPSF CCCCCCCHHHCCCCC	36.25	21712547
353	Phosphorylation	KFPQRSYTAPNTSFN ECCCCCCCCCCCCCC	36.56	29996109
481	Phosphorylation	LSCHRNLSFSESLPT HCCCCCCCCCCCCCC	30.21	29996109
488	Phosphorylation	SFSESLPTAEDQVHN CCCCCCCCHHHHHHH	48.23	29996109
501	Phosphorylation	HNNHCAVSPSRRSSS HHCCCCCCCCCCCCC	9.91	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of STE7_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of STE7_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of STE7_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RAN1_SCHPO	ran1	physical	10835379
MEI2_SCHPO	mei2	physical	10835379

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.