dbPTM

STE7_CANAL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	STE7_CANAL
UniProt AC	Q5A6T5
Protein Name	Serine/threonine-protein kinase STE7 homolog
Gene Name	HST7
Organism	Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
Sequence Length	589
Subcellular Localization
Protein Description
Protein Sequence	MTRTTRIDTQEATKHKDLPPVPSPLSLSSNPNPECLMESKSLGRKNFKKLSLDASPVKSTSGSLRSSDMMSIKEPTSLRQKRQRPPPILHLPTASSSATSTPTSNITGSSSASSIQFAQKSPGSGVIVSQTLSRPSSAGGIPSSGYSSLNVNQSNRNVDPDNVVSTDMILNQISNLDLTSMNHHRQHYQNSHHHLPTTNRKRQTVISSISPTKSSAASSSLEPQIQSLPASSQSPIATTSSLKLNNKDLLTLKQLGSGNSGSVSKILHIPTQKTMAKKIIHIDSKSVIQTQIIRELRILHECHSPYIIEFYGACLNNNNTIVICMEYCNCGSLDKILPLCENKQFPTFVLKKLSFAILSGLTYLYTTHKIIHRDIKPNNVLMTHKGEFKLCDFGVSRELTNSLAMADTFVGTSMYMSPERIQGLDYGVKSDVWSTGLMLIELASGVPVWSEDDNNNDDDEDDEDDAYVRQGSIAAERNGQNSPSRSRKNKQKGNGYNSYNGPEGILDLLQRIVNEDAPTLTNKINPVTKLPYDKYLCQFIDLCLIKDDSVRKTPWQLLEDKEHFFKGVEEGVYDKEHKSWAKKIRKCKV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
55	Phosphorylation	KKLSLDASPVKSTSG CCCCCCCCCCCCCCC	29.87	25750214
210	Phosphorylation	QTVISSISPTKSSAA CEEEEEECCCCCCCC	28.59	25750214
212	Phosphorylation	VISSISPTKSSAASS EEEEECCCCCCCCCC	36.45	19547744
271	Phosphorylation	SKILHIPTQKTMAKK HHEEECCCCCCCCCE	41.94	19547744
402	Phosphorylation	VSRELTNSLAMADTF CCHHHHHHHHHHCCC	19.67	-
408	Phosphorylation	NSLAMADTFVGTSMY HHHHHHCCCCCCCCC	15.64	-
472	Phosphorylation	DAYVRQGSIAAERNG HHHHHHHHHHHHHCC	10.75	19547744

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of STE7_CANAL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of STE7_CANAL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of STE7_CANAL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
ERK1_CANAL	CEK1	physical	20719741

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of STE7_CANAL

Related Literatures of Post-Translational Modification