ERK1_CANAL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ERK1_CANAL
• UniProt AC: Q5A1D3
• Protein Name: Extracellular signal-regulated kinase 1
• Gene Name: CEK1
• Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
• Sequence Length: 421
• Protein Sequence: MNIDQHHQLQQQHQQQMLQQQAQAQAQAQAQAQQQQQQQQQAAAAAAAANAAATTSSSPRQVSFNVSDHYQILEIVGEGAYGIVCSAIHKPSQQKVAIKKIEPFERSMLCLRTLRELKLLKHFNHENIISILAIQRPINYESFNEIYLIQELMETDLHRVIRTQNLSDDHIQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNSNCDLKICDFGLARSIASQEDNYGFMTEYVATRWYRAPEIMLTFQEYTTAIDVWSVGCILAEMLSGRPLFPGRDYHNQLWLIMEVLGTPNMEDYYNIKSKRAREYIRSLPFCKKIPFSELFANTNNNTSTSTSNTGGRTNINPLALDLLEKLLIFNPAKRITVEDALKHPYLQLYHDPNDEPISDKIPEDFFDFDKMKDQLTIEDLKKLLYEEIMKPL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
230	Phosphorylation	EDNYGFMTEYVATRW CCCCCHHHHHHHHCC	2.12	-
231	Phosphorylation	DNYGFMTEYVATRWY CCCCHHHHHHHHCCC	23.15	-
232	Phosphorylation	NYGFMTEYVATRWYR CCCHHHHHHHHCCCC	26.65	-
233	Phosphorylation	YGFMTEYVATRWYRA CCHHHHHHHHCCCCC	6.04	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ERK1_CANAL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ERK1_CANAL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ERK1_CANAL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
STE7_CANAL	HST7	physical	20719741
CPH1_CANAL	CPH1	physical	20719741

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.