ST1C3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ST1C3_HUMAN
• UniProt AC: Q6IMI6
• Protein Name: Sulfotransferase 1C3
• Gene Name: SULT1C3
• Organism: Homo sapiens (Human).
• Sequence Length: 304
• Subcellular Localization: Cytoplasm.
• Protein Description: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor and has low sulphotransferase activity towards various substrates with alcohol groups (in vitro). May catalyze the sulfate conjugation of xenobiotic compounds and endogenous substrates..
• Protein Sequence: MAKIEKNAPTMEKKPELFNIMEVDGVPTLILSKEWWEKVCNFQAKPDDLILATYPKSGTTWMHEILDMILNDGDVEKCKRAQTLDRHAFLELKFPHKEKPDLEFVLEMSSPQLIKTHLPSHLIPPSIWKENCKIVYVARNPKDCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKVVGGSWFDHVKGWWAAKDMHRILYLFYEDIKKDPKREIEKILKFLEKDISEEILNKIIYHTSFDVMKQNPMTNYTTLPTSIMDHSISPFMRKGMPGDWKNYFTVAQNEEFDKDYQKKMAGSTLTFRTEI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
234	Phosphorylation	EILNKIIYHTSFDVM HHHHHHHHHCCHHHH	11.52	22210691
247	Phosphorylation	VMKQNPMTNYTTLPT HHHHCCCCCCCCCCC	26.74	25072903
249	Phosphorylation	KQNPMTNYTTLPTSI HHCCCCCCCCCCCHH	7.61	25072903
250	Phosphorylation	QNPMTNYTTLPTSIM HCCCCCCCCCCCHHH	24.75	25072903
251	Phosphorylation	NPMTNYTTLPTSIMD CCCCCCCCCCCHHHC	22.00	25072903
254	Phosphorylation	TNYTTLPTSIMDHSI CCCCCCCCHHHCCCC	33.72	25072903
255	Phosphorylation	NYTTLPTSIMDHSIS CCCCCCCHHHCCCCC	17.61	25072903
260	Phosphorylation	PTSIMDHSISPFMRK CCHHHCCCCCHHHHC	22.09	25072903
262	Phosphorylation	SIMDHSISPFMRKGM HHHCCCCCHHHHCCC	18.33	25072903
289	Phosphorylation	NEEFDKDYQKKMAGS CHHCCHHHHHHHCCC	28.15	-
292	Ubiquitination	FDKDYQKKMAGSTLT CCHHHHHHHCCCEEE	20.61	-
299	Phosphorylation	KMAGSTLTFRTEI-- HHCCCEEEEECCC--	15.91	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ST1C3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ST1C3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ST1C3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VATA_HUMAN	ATP6V1A	physical	26344197

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.