SPAS1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SPAS1_HUMAN
• UniProt AC: Q496A3
• Protein Name: Spermatogenesis-associated serine-rich protein 1
• Gene Name: SPATS1
• Organism: Homo sapiens (Human).
• Sequence Length: 300
• Protein Sequence: MSPSMLTGNSPRGCRLPSISSTTCGRQLEKVPEKRDSGMTEVERTYSANCSDFLESKGCFANTTPSGKSVSSSSSVETGPSVSEPPGLPRVSAYVDTTADLDRKLSFSHSDHSSEMSLPEVQKDKYPEEFSLLKLQTKDGHRPEWTFYPRFSSNIHTYHVGKQCFFNGVFLGNKRSLSERTVDKCFGRKKYDIDPRNGIPKLTPGDNPYMYPEQSKGFHKAGSMLPPVNFSIVPYEKKFDTFIPLEPLPQIPNLPFWVKEKANSLKNEIQEVEELDNWQPAVPLMHMLHLSGALDFPRQS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
18	Phosphorylation	PRGCRLPSISSTTCG CCCCCCCCCCCCCCC	39.43	25332170
20	Phosphorylation	GCRLPSISSTTCGRQ CCCCCCCCCCCCCCC	26.43	25332170
56	Phosphorylation	NCSDFLESKGCFANT CHHHHHHHCCCEEEC	36.17	22468782
63	Phosphorylation	SKGCFANTTPSGKSV HCCCEEECCCCCCCC	36.33	22468782
69	Phosphorylation	NTTPSGKSVSSSSSV ECCCCCCCCCCCCCC	30.66	25693802
71	Phosphorylation	TPSGKSVSSSSSVET CCCCCCCCCCCCCCC	31.43	22468782
72	Phosphorylation	PSGKSVSSSSSVETG CCCCCCCCCCCCCCC	31.89	22468782
73	Phosphorylation	SGKSVSSSSSVETGP CCCCCCCCCCCCCCC	21.08	25693802
74	Phosphorylation	GKSVSSSSSVETGPS CCCCCCCCCCCCCCC	40.11	25693802
75	Phosphorylation	KSVSSSSSVETGPSV CCCCCCCCCCCCCCC	26.39	25693802
78	Phosphorylation	SSSSSVETGPSVSEP CCCCCCCCCCCCCCC	52.84	22468782
81	Phosphorylation	SSVETGPSVSEPPGL CCCCCCCCCCCCCCC	39.35	22468782
83	Phosphorylation	VETGPSVSEPPGLPR CCCCCCCCCCCCCCC	49.04	22468782
113	Phosphorylation	SFSHSDHSSEMSLPE CCCCCCCCCCCCCCH	32.74	-
114	Phosphorylation	FSHSDHSSEMSLPEV CCCCCCCCCCCCCHH	33.62	-
126	Phosphorylation	PEVQKDKYPEEFSLL CHHHHCCCHHHHEEE	26.47	28509920
131	Phosphorylation	DKYPEEFSLLKLQTK CCCHHHHEEEEEEEC	35.75	24719451
148	Phosphorylation	HRPEWTFYPRFSSNI CCCCCEECCCCCCCC	6.02	28331001
152	Phosphorylation	WTFYPRFSSNIHTYH CEECCCCCCCCEEEE	24.61	-
153	Phosphorylation	TFYPRFSSNIHTYHV EECCCCCCCCEEEEC	36.77	-
178	Phosphorylation	LGNKRSLSERTVDKC CCCCCCCCHHHHHHH	26.69	22617229
184	Acetylation	LSERTVDKCFGRKKY CCHHHHHHHHCCCCC	27.42	12654531
191	Phosphorylation	KCFGRKKYDIDPRNG HHHCCCCCCCCCCCC	22.59	20049867
203	Phosphorylation	RNGIPKLTPGDNPYM CCCCCCCCCCCCCCC	31.21	-
209	Phosphorylation	LTPGDNPYMYPEQSK CCCCCCCCCCHHHCC	18.61	-
211	Phosphorylation	PGDNPYMYPEQSKGF CCCCCCCCHHHCCCC	9.58	-
215	Phosphorylation	PYMYPEQSKGFHKAG CCCCHHHCCCCCCCC	32.84	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SPAS1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SPAS1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SPAS1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SPG7_HUMAN	SPG7	physical	21988832

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.