SOX14_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SOX14_HUMAN
• UniProt AC: O95416
• Protein Name: Transcription factor SOX-14
• Gene Name: SOX14
• Organism: Homo sapiens (Human).
• Sequence Length: 240
• Subcellular Localization: Nucleus .
• Protein Description: Acts as a negative regulator of transcription..
• Protein Sequence: MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAPEKARAFLPPASAPYSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGYQNGAFGSLSCPSQHTHTHPSPTNPGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MSKPSDHIKRPM ---CCCCCHHCCCCH	45.62	27251275
19	Phosphorylation	MNAFMVWSRGQRRKM HHCHHHCCHHHHHHH	18.34	30631047
36	Phosphorylation	ENPKMHNSEISKRLG HCCCCCHHHHHHHHC	22.94	-
40	Acetylation	MHNSEISKRLGAEWK CCHHHHHHHHCHHHH	58.25	18585087
98	Phosphorylation	RYVFPLPYLGDTDPL CEEECCCCCCCCCHH	30.88	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SOX14_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SOX14_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SOX14_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NAIF1_HUMAN	NAIF1	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.