NAIF1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NAIF1_HUMAN
• UniProt AC: Q69YI7
• Protein Name: Nuclear apoptosis-inducing factor 1
• Gene Name: NAIF1
• Organism: Homo sapiens (Human).
• Sequence Length: 327
• Subcellular Localization: Nucleus .
• Protein Description: Induces apoptosis..
• Protein Sequence: MAVPAKKRKMNFSEREVEIIVEELELKKHLLVNHFNAGVPLAAKSAAWHGILRRVNAVATCRRELPEVKKKWSDLKTEVRRKVAQVRAAVEGGEAPGPTEEDGAGGPGTGGGSGGGGPAVAPVLLTPMQQRICNLLGEATIISLPSTTEIHPVALGPSATAAAATVTLTQIPTETTYHTLEEGVVEYCTAEAPPPLPPETPVDMMAQHADTSVKPQALKSRIALNSAKLIQEQRVTNLHVKEIAQHLEQQNDLLQMIRRSQEVQACAQERQAQAMEGTQAALSVLIQVLRPMIKDFRRYLQSNTANPAPASDPGQVAQNGQPDSIIQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
28	Ubiquitination	VEELELKKHLLVNHF HHHHHHHHHHHHHCC	52.70	-
76	Ubiquitination	KKKWSDLKTEVRRKV HHHHHHHHHHHHHHH	47.86	-
228	Ubiquitination	RIALNSAKLIQEQRV HHHHCHHHHHHHHHC	46.04	-
236	Phosphorylation	LIQEQRVTNLHVKEI HHHHHHCCHHHHHHH	33.96	27251275
278	Phosphorylation	QAQAMEGTQAALSVL HHHHHHHHHHHHHHH	11.17	24043423

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NAIF1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NAIF1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NAIF1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of NAIF1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.