dbPTM

SMC5_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SMC5_ARATH
UniProt AC	Q9LFS8
Protein Name	Structural maintenance of chromosomes protein 5
Gene Name	SMC5
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	1053
Subcellular Localization	Nucleus. Chromosome. Associates with chromatin..
Protein Description	Core component of the SMC5-SMC6 complex that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids..
Protein Sequence	MSERRAKRPKISRGEDDFLPGNIIEIELHNFMTFNHLVCKPGSRLNLVIGPNGSGKSSLVCAIALCLGGEPQLLGRATSVGAYVKRGEDSGYVKISLRGNTREENLTIFRKIDTRNKSEWMFNGSTVSKKDIVEIIQKFNIQVNNLTQFLPQDRVCEFAKLTPVQLLEETEKAVGDPQLPVHHRALVEKSRDLKQLERAVAKNGETLNQLKALVDEQEKDVERVRQRELFLTKVDSMKKKLPWLKYDMKKAEYMDAKKRMKEAEKKLDEAAKNLNSMKEPIEKQKKEKAETDSKCKKVKNLMDANGRNRCHLLEKEDEADARVVATYKELEELKKQEEHRQERILKATEDLVAAERELQNLPVYERPVAKLEELSSQVTELHHSINGKKNQKEDNEKLLSQKRYTLRQCVDKLKDMENANNKLLKALANSGADRIFDAYQWVQQNRHEFKREVYGPVLVEVNVPNRENACFLEGHVSFYIWKSFITQDPEDRDLLVKNLKRFDVPVLNYVGNSGNQKAPFHISDQMRSLGIHARLDQIFDAPDAVKEVLNSQFGLEDSYIGSKITDQRAEEVYKLGIKDFWTPDNHYRWSSSRYGGHSSASVDSVYQSRLLLCGVDVGELEKLRSRKEELEDSILFMEETHKSLQTEQRRLEEEAAKLHKEREEIVNVSYLEKKKRRELESRYQQRKTKLESLEQEEDMDASVAKLIDQASRANADRYTYAINLKKLLVEAVAHKWSYAEKHMASIELERKIRESEINIKQYEKTAQQLSLAVEYCKKEVEGKQQRLATAKRDAESVATITPELKKEFMEMPTTVEELEAAIQDNLSQANSILFINENILQEYEHRQSQIYTISTKLETDKRDLSICMKEIDSLKEKWLPTLRQLVGQINETFSHNFQEMAVAGEVSLDERDTDFDQYGIHIKVKFRESGQLQVLSSHHQSGGERSVSTILYLVSLQDLTNCPFRVVDEINQGMDPINERKMFQQLVRAASQPNTPQCFLLTPKLLPELEYSEACSILNIMNGPYIAEPSKVWSLGDSWGSLNRRRTEASQCS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of SMC5_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SMC5_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SMC5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SMC5_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
NSE2_ARATH	HPY2	physical	23426194

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SMC5_ARATH

Related Literatures of Post-Translational Modification