SLPI_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SLPI_HUMAN
• UniProt AC: P03973
• Protein Name: Antileukoproteinase
• Gene Name: SLPI
• Organism: Homo sapiens (Human).
• Sequence Length: 132
• Subcellular Localization: Secreted .
• Protein Description: Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. [PubMed: 3533531]
• Protein Sequence: MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGKKRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCMGMCGKSCVSPVKA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
78	Phosphorylation	KCLDPVDTPNPTRRK EECCCCCCCCCCCCC	25.79	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SLPI_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SLPI_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SLPI_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PLS1_HUMAN	PLSCR1	physical	10869562
GRN_HUMAN	GRN	physical	12526812
FAM9B_HUMAN	FAM9B	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.