SKOR_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SKOR_ARATH
• UniProt AC: Q9M8S6
• Protein Name: Potassium channel SKOR
• Gene Name: SKOR
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 828
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Description: Highly selective outward-rectifying potassium channel. Involved in potassium release into the xylem sap toward the shoots. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by depolarization. The voltage-dependence of the channel is abolished by internal or external acidification. May interact with the cytoskeleton or with regulatory proteins..
• Protein Sequence: MGGSSGGGVSYRSGGESDVELEDYEVDDFRDGIVESRGNRFNPLTNFLGLDFAGGSGGKFTVINGIRDISRGSIVHPDNRWYKAWTMFILIWALYSSFFTPLEFGFFRGLPENLFILDIAGQIAFLVDIVLTFFVAYRDSRTYRMIYKRSSIALRYLKSTFIIDLLACMPWDIIYKAAGEKEEVRYLLLIRLYRVHRVILFFHKMEKDIRINYLFTRIVKLIFVELYCTHTAACIFYYLATTLPASQEGYTWIGSLKLGDYSYSKFREIDLWTRYTTSMYFAVVTMATVGYGDIHAVNMREMIFAMVYISFDMILGAYLIGNMTALIVKGSKTERFRDKMADIMRYMNRNKLGRNIRGQITGHLRLQYESSYTEAAVLQDIPVSIRAKIAQTLYLPYIEKVPLFRGCSSEFINQIVIRLHEEFFLPGEVIMEQGSVVDQLYFVCHGVLEEIGITKDGSEEIVAVLQPDHSFGEISILCNIPQPYTVRVAELCRILRLDKQSFMNILEIFFHDGRRILNNLLEGKESNVRIKQLESDITFHISKQEAELALKLNSAAFYGDLYQLKSLIRAGGDPNKTDYDGRSPLHLAASRGYEDITLYLIQESVDVNIKDKLGSTPLLEAIKNGNDRVAALLVKEGATLNIENAGTFLCTVVAKGDSDFLKRLLSNGIDPNSKDYDHRTPLHVAASEGFYVLAIQLVEASANVLAKDRWGNTPLDEALGCGNKMLIKLLEDAKNSQISSFPSGSKEPKDKVYKKKCTVYFSHPGDSKEKRRRGIVLWVPRSIEELIRTAKEQLNVPEASCVLSEDEAKIIDVDLISDGQKLYLAVET

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
275	Phosphorylation	EIDLWTRYTTSMYFA CCCCHHHHCHHHHEE	13.64	22074104
288	Phosphorylation	FAVVTMATVGYGDIH EEEEEHHHCCCCCEE	12.02	22074104
308	Phosphorylation	EMIFAMVYISFDMIL HHHHHHHHHHHHHHH	4.27	23776212
310	Phosphorylation	IFAMVYISFDMILGA HHHHHHHHHHHHHHH	9.48	23776212
318	Phosphorylation	FDMILGAYLIGNMTA HHHHHHHHHHCCCEE	9.32	23776212
324	Phosphorylation	AYLIGNMTALIVKGS HHHHCCCEEEEECCC	23.47	23776212
736	Phosphorylation	LLEDAKNSQISSFPS HHHHHHHCCCCCCCC	28.34	19880383
739	Phosphorylation	DAKNSQISSFPSGSK HHHHCCCCCCCCCCC	20.49	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SKOR_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SKOR_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SKOR_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SKOR_ARATH	SKOR	physical	15298894
GORK_ARATH	GORK	physical	15298894

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.