| UniProt ID | SH3Y1_HUMAN | |
|---|---|---|
| UniProt AC | Q96HL8 | |
| Protein Name | SH3 domain-containing YSC84-like protein 1 | |
| Gene Name | SH3YL1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 342 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVTARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNLTLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFYCQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Phosphorylation | -MNNPIPSNLKSEAK -CCCCCCCCHHHHHH | 56.36 | 23186163 | |
| 11 | Phosphorylation | PIPSNLKSEAKKAAK CCCCCHHHHHHHHHH | 46.05 | 23186163 | |
| 11 (in isoform 3) | Phosphorylation | - | 46.05 | 25690035 | |
| 11 (in isoform 4) | Phosphorylation | - | 46.05 | 25690035 | |
| 180 | Phosphorylation | KETNRKFYCQDIRAY CCCCCCEEECHHHHH | 7.70 | - | |
| 269 | Phosphorylation | NRNEYKLYPGLSSYH CCCCCCCCCCCCHHH | 7.36 | 27642862 | |
| 274 | Phosphorylation | KLYPGLSSYHERVGN CCCCCCCHHHHHHCC | 35.24 | 27642862 | |
| 292 | Phosphorylation | PIEVTALYSFEGQQP CEEEEEEEEECCCCC | 14.62 | 27642862 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SH3Y1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SH3Y1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SH3Y1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SH319_HUMAN | SH3D19 | physical | 12615363 | |
| VIME_HUMAN | VIM | physical | 16169070 | |
| ZBT7B_HUMAN | ZBTB7B | physical | 25416956 | |
| VP37B_HUMAN | VPS37B | physical | 25416956 | |
| SH319_HUMAN | SH3D19 | physical | 25416956 | |
| VP37B_HUMAN | VPS37B | physical | 21516116 | |
| SH319_HUMAN | SH3D19 | physical | 28514442 | |
| P3C2B_HUMAN | PIK3C2B | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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