dbPTM

SERC_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SERC_DROME
UniProt AC	Q9VAN0
Protein Name	Probable phosphoserine aminotransferase
Gene Name	CG11899
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	364
Subcellular Localization
Protein Description	Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine..
Protein Sequence	MVINFAAGPAKLPEEVLKEVQENLVNCNGSGISVMEMSHRSSNYAKIHDATISDLRELLNVPSNYKILLMQGGGTGQFAAVALNLIGKTGTADYVITGSWSAKAAKEAAQYGTVNAVLPKLAKYTTVPRQETWKLDPNASYVYYCDNETVEGVEFDFVPEVPAGVPLVADMSSNFLSRPFDVSKFGVIYAGAQKNIGPAGTTVIIVRDDLIGKHLKITPSILNFEQMDKNNSLLNTPPTFGIYVMGLVFKWIKRNGGVAGMAKLAAAKSKLIYDTINQSNGFYYCPVDVNVRSRMNVPFRIGSASGDDALEKEFLSKAEAEGMIQLKGHRSVGGIRASLYNAVTLAETQQLANLMLAFYKNNKN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	Phosphorylation	NLVNCNGSGISVMEM HHCCCCCCCEEEEEE	20.97	22817900
42	Phosphorylation	MEMSHRSSNYAKIHD EEECCCCCCCCEEEE	33.54	22817900
44	Phosphorylation	MSHRSSNYAKIHDAT ECCCCCCCCEEEECC	15.95	22817900
46	Ubiquitination	HRSSNYAKIHDATIS CCCCCCCEEEECCHH	30.16	31113955
194	N6-(pyridoxal phosphate)lysine	VIYAGAQKNIGPAGT EEEEECCCCCCCCCC	50.42	-
194	Other	VIYAGAQKNIGPAGT EEEEECCCCCCCCCC	50.42	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SERC_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SERC_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SERC_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
MSRB_DROME	SelR	physical	14605208

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SERC_DROME

Related Literatures of Post-Translational Modification