SEC6_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SEC6_ARATH
• UniProt AC: Q94AI6
• Protein Name: Exocyst complex component SEC6
• Gene Name: SEC6
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 752
• Subcellular Localization: Cytoplasm, cytosol . Cell membrane . Cytoplasm, cytoskeleton, phragmoplast . Secreted, cell wall . Secreted, exosome . During cytokinesis, localizes to the nascent cell plate and later to the cell plate insertion site and along the post-cytokinetic w
• Protein Description: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall..
• Protein Sequence: MMVEDLGVEAKEAAVREVAKLLPLPELLQSISSIKADYIARQQANDAQLSTMVAEQVEQAQAGLESLSSSEKTIYELRDNFISIDKLCQECQTLIDNHDQIKLLSNARNNLNKTLKDVEGMMSISVEAAAARDSLSDDKEIVNTYERLTALDGKRRFALAAAGEEVGRLREYFEDVDRTWETFEKTLWGHVSNYYKLSKESPQTLVRALRVVEMQEILDQQLAEEAAEAEGEGAMASVANPRRPGKKSTTTSASSKGLAQQKLKVQGKGYKDKCYEQIRKAVEDRFNRLLTLVFEDLKAALEEARMIGEELGDIYDYVAPCFPPRYEIFQLMVNLYTERFIQMLRLLSDRANDLTNIEILKVTGWVVEYQENLIALGVDDSLAQVCSESGSMDPLMNAYVERMQATTKKWYMNILEADKVQPPKKTEEGKLYTPAAVDLFRILGEQVQIVRDNSTDVMLYRIALAIIQVMIDFQAAEKKRVDEPASDIGLEPLCAMINNNLRCYDLAMELSNSTLEALPQNYAEQVNFEDTCKGFLEVAKEAVHQTVRVIFEDPGVQELLVKLYQKEWCEGQVTEYLVATFGDYFTDVKMYVEERSFRRFVEACLEETVVVYVDHLLTQKNYIKEETIERMRLDEEVLMDFFREYISASKVESRIRIMSDLRELASAESLDAFTLVYSNILEHQPDCPAEVVEKLVSLREGIPRKDTKEVVQECKEIYENTLVDGNPPKTGFVFPRVKCLTASKGSMWRKLT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MMVEDLGV -------CCHHHHCH		22223895
32	Phosphorylation	PELLQSISSIKADYI HHHHHHHHHHHHHHH		23111157
125	Phosphorylation	VEGMMSISVEAAAAR HHHHHHHHHHHHHHH		22074104
134	Phosphorylation	EAAAARDSLSDDKEI HHHHHHHCCCCCHHH		22074104
254	Phosphorylation	KSTTTSASSKGLAQQ CCCCCCCCHHCHHHH		26658240
255	Phosphorylation	STTTSASSKGLAQQK CCCCCCCHHCHHHHH		26658240
659	Phosphorylation	ESRIRIMSDLRELAS HHHHHHCHHHHHHHC		22074104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SEC6_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SEC6_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SEC6_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KEULE_ARATH	KEU	physical	23702595
SEC8_ARATH	SEC8	physical	18492870

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.