| UniProt ID | SDSL_HUMAN | |
|---|---|---|
| UniProt AC | Q96GA7 | |
| Protein Name | Serine dehydratase-like | |
| Gene Name | SDSL | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 329 | |
| Subcellular Localization | ||
| Protein Description | Has low serine dehydratase and threonine dehydratase activity.. | |
| Protein Sequence | MDGPVAEHAKQEPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEMAKKGCRHLVCSSGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLRAQELAKRDGWENVPPFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLAGVVAGLLEVGWQHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQVCKIHSEVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPSLTSVVVIVCGGNNINSRELQALKTHLGQV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MDGPVAEH -------CCCCHHHH | 14.00 | 22223895 | |
| 44 | Phosphorylation | KCENVQPSGSFKIRG EEECCCCCCCEEECC | 29.94 | 24275569 | |
| 46 | Phosphorylation | ENVQPSGSFKIRGIG ECCCCCCCEEECCHH | 27.92 | 28857561 | |
| 48 | Methylation | VQPSGSFKIRGIGHF CCCCCCEEECCHHHH | 32.94 | - | |
| 48 | N6-(pyridoxal phosphate)lysine | VQPSGSFKIRGIGHF CCCCCCEEECCHHHH | 32.94 | - | |
| 48 | Other | VQPSGSFKIRGIGHF CCCCCCEEECCHHHH | 32.94 | - | |
| 227 | Ubiquitination | PDITSVAKSLGAKTV CCHHHHHHHCCCHHH | 44.02 | 21890473 | |
| 232 | Ubiquitination | VAKSLGAKTVAARAL HHHHCCCHHHHHHHH | 41.56 | - | |
| 242 | Sulfoxidation | AARALECMQVCKIHS HHHHHHHHHHHHHHH | 2.15 | 30846556 | |
| 284 | Phosphorylation | GAALAAIYSGLLRRL HHHHHHHHHHHHHHH | 7.61 | 24043423 | |
| 285 | Phosphorylation | AALAAIYSGLLRRLQ HHHHHHHHHHHHHHH | 19.49 | 24043423 | |
| 302 | Phosphorylation | GCLPPSLTSVVVIVC CCCCCCCCEEEEEEE | 24.66 | - | |
| 303 | Phosphorylation | CLPPSLTSVVVIVCG CCCCCCCEEEEEEEC | 20.43 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SDSL_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SDSL_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SDSL_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SDSL_HUMAN | SDSL | physical | 16189514 | |
| SDSL_HUMAN | SDSL | physical | 25416956 | |
| SDSL_HUMAN | SDSL | physical | 21516116 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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