S35F5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: S35F5_HUMAN
• UniProt AC: Q8WV83
• Protein Name: Solute carrier family 35 member F5
• Gene Name: SLC35F5
• Organism: Homo sapiens (Human).
• Sequence Length: 523
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: Putative solute transporter..
• Protein Sequence: MVPPRRHRGAGRPGVLSSSPPFRLRSAKFSGIALEDLRRALKTRLQMVCVFVMNRMNSQNSGFTQRRRMALGIVILLLVDVIWVASSELTSYVFTQYNKPFFSTFAKTSMFVLYLLGFIIWKPWRQQCTRGLRGKHAAFFADAEGYFAACTTDTTMNSSLSEPLYVPVKFHDLPSEKPESTNIDTEKTPKKSRVRFSNIMEIRQLPSSHALEAKLSRMSYPVKEQESILKTVGKLTATQVAKISFFFCFVWFLANLSYQEALSDTQVAIVNILSSTSGLFTLILAAVFPSNSGDRFTLSKLLAVILSIGGVVLVNLAGSEKPAGRDTVGSIWSLAGAMLYAVYIVMIKRKVDREDKLDIPMFFGFVGLFNLLLLWPGFFLLHYTGFEDFEFPNKVVLMCIIINGLIGTVLSEFLWLWGCFLTSSLIGTLALSLTIPLSIIADMCMQKVQFSWLFFAGAIPVFFSFFIVTLLCHYNNWDPVMVGIRRIFAFICRKHRIQRVPEDSEQCESLISMHSVSQEDGAS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	AGRPGVLSSSPPFRL CCCCCCCCCCCCCCC	26.77	29083192
18	Phosphorylation	GRPGVLSSSPPFRLR CCCCCCCCCCCCCCC	42.58	28555341
19	Phosphorylation	RPGVLSSSPPFRLRS CCCCCCCCCCCCCCC	32.96	29083192
30	Phosphorylation	RLRSAKFSGIALEDL CCCCCCCCCCCHHHH	28.69	21955146
165	Phosphorylation	SSLSEPLYVPVKFHD CCCCCCEEEEEECCC	17.27	26437602
177	Ubiquitination	FHDLPSEKPESTNID CCCCCCCCCCCCCCC	59.42	-
187	Ubiquitination	STNIDTEKTPKKSRV CCCCCCCCCCCCCCC	72.69	-
188	Phosphorylation	TNIDTEKTPKKSRVR CCCCCCCCCCCCCCC	33.82	28555341
192	Phosphorylation	TEKTPKKSRVRFSNI CCCCCCCCCCCCCCC	41.98	26270265
197	Phosphorylation	KKSRVRFSNIMEIRQ CCCCCCCCCCHHHHC	18.19	26270265
207	Phosphorylation	MEIRQLPSSHALEAK HHHHCCCCCHHHHHH	43.26	14702039
208	Phosphorylation	EIRQLPSSHALEAKL HHHCCCCCHHHHHHH	15.73	28857561
214	Ubiquitination	SSHALEAKLSRMSYP CCHHHHHHHHCCCCC	37.31	-
216	Phosphorylation	HALEAKLSRMSYPVK HHHHHHHHCCCCCHH	25.82	-
223	Ubiquitination	SRMSYPVKEQESILK HCCCCCHHHHHHHHH	49.53	-
227	Phosphorylation	YPVKEQESILKTVGK CCHHHHHHHHHHHHH	32.68	24719451
230	Ubiquitination	KEQESILKTVGKLTA HHHHHHHHHHHHCHH	39.22	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of S35F5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of S35F5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of S35F5_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SHOC2_HUMAN	SHOC2	physical	27173435

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.