S35D3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: S35D3_HUMAN
• UniProt AC: Q5M8T2
• Protein Name: Solute carrier family 35 member D3
• Gene Name: SLC35D3
• Organism: Homo sapiens (Human).
• Sequence Length: 416
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: May play a role in hemostasis as a regulator of the biosynthesis of platelet-dense granules..
• Protein Sequence: MRQLCRGRVLGISVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGLIAVPPFGLSLARSFAGVAVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVICSFASTDSIHAWTFPGWKDPAMVCIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCVAKFMETRKQSNYEDLEAQPRGEEAQLSGDQLPFVMEELPGEGGNGRSEGGEAAGGPAQESRQEVRGSPRGVPLVAGSSEEGSRRSLKDAYLEVWRLVRGTRYMKKDYLIENEELPSP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
49	Phosphorylation	TLVQCLTSSTAALSL HHHHHHCCCHHHHHH	16.85	-
77	Phosphorylation	FGLSLARSFAGVAVL CCHHHHHHHHHHHHH	17.53	25332170
92	Phosphorylation	STLQSSLTLWSLRGL HHHHHHHHHHHHCCC	28.29	25332170
95	Phosphorylation	QSSLTLWSLRGLSLP HHHHHHHHHCCCCCC	15.99	24719451
311	Phosphorylation	ETRKQSNYEDLEAQP HHHHHCCHHHHHCCC	18.96	25884760
366	Phosphorylation	SRQEVRGSPRGVPLV HHHHHCCCCCCCCCC	10.81	-
377	Phosphorylation	VPLVAGSSEEGSRRS CCCCCCCCCCCCCCC	38.46	-
389	Phosphorylation	RRSLKDAYLEVWRLV CCCHHHHHHHHHHHH	17.33	-
415	Phosphorylation	IENEELPSP------ ECCCCCCCC------	56.73	29970186

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of S35D3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of S35D3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of S35D3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GPCP1_HUMAN	GPCPD1	physical	28514442
VPP1_HUMAN	ATP6V0A1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.