GPCP1_HUMAN - dbPTM
GPCP1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GPCP1_HUMAN
UniProt AC Q9NPB8
Protein Name Glycerophosphocholine phosphodiesterase GPCPD1
Gene Name GPCPD1
Organism Homo sapiens (Human).
Sequence Length 672
Subcellular Localization Cytoplasm, cytosol.
Protein Description May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity..
Protein Sequence MTPSQVAFEIRGTLLPGEVFAICGSCDALGNWNPQNAVALLPENDTGESMLWKATIVLSRGVSVQYRYFKGYFLEPKTIGGPCQVIVHKWETHLQPRSITPLESEIIIDDGQFGIHNGVETLDSGWLTCQTEIRLRLHYSEKPPVSITKKKLKKSRFRVKLTLEGLEEDDDDRVSPTVLHKMSNSLEISLISDNEFKCRHSQPECGYGLQPDRWTEYSIQTMEPDNLELIFDFFEEDLSEHVVQGDALPGHVGTACLLSSTIAESGKSAGILTLPIMSRNSRKTIGKVRVDYIIIKPLPGYSCDMKSSFSKYWKPRIPLDVGHRGAGNSTTTAQLAKVQENTIASLRNAASHGAAFVEFDVHLSKDFVPVVYHDLTCCLTMKKKFDADPVELFEIPVKELTFDQLQLLKLTHVTALKSKDRKESVVQEENSFSENQPFPSLKMVLESLPEDVGFNIEIKWICQQRDGMWDGNLSTYFDMNLFLDIILKTVLENSGKRRIVFSSFDADICTMVRQKQNKYPILFLTQGKSEIYPELMDLRSRTTPIAMSFAQFENLLGINVHTEDLLRNPSYIQEAKAKGLVIFCWGDDTNDPENRRKLKELGVNGLIYDRIYDWMPEQPNIFQVEQLERLKQELPELKSCLCPTVSRFVPSSLCGESDIHVDANGIDNVENA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
55PhosphorylationESMLWKATIVLSRGV
CCCEEEEEEEEECCC		14.1121712546
59PhosphorylationWKATIVLSRGVSVQY
EEEEEEEECCCEEEE		18.9821712546
68PhosphorylationGVSVQYRYFKGYFLE
CCEEEEEEEEEECCC		12.52-
72PhosphorylationQYRYFKGYFLEPKTI
EEEEEEEECCCCCCC		12.94-
139PhosphorylationEIRLRLHYSEKPPVS
EEEEEEECCCCCCCC		24.1029083192
140PhosphorylationIRLRLHYSEKPPVSI
EEEEEECCCCCCCCC		28.5329083192
146PhosphorylationYSEKPPVSITKKKLK
CCCCCCCCCCHHHHC		30.2529083192
148PhosphorylationEKPPVSITKKKLKKS
CCCCCCCCHHHHCCC		29.3429083192
155PhosphorylationTKKKLKKSRFRVKLT
CHHHHCCCCEEEEEE		34.7623911959
162PhosphorylationSRFRVKLTLEGLEED
CCEEEEEEECCCCCC		19.6223403867
173MethylationLEEDDDDRVSPTVLH
CCCCCCCCCCHHHHH		37.50-
175PhosphorylationEDDDDRVSPTVLHKM
CCCCCCCCHHHHHHH		18.7530266825
177PhosphorylationDDDRVSPTVLHKMSN
CCCCCCHHHHHHHCC		28.3530266825
183PhosphorylationPTVLHKMSNSLEISL
HHHHHHHCCCEEEEE		28.2429978859
185PhosphorylationVLHKMSNSLEISLIS
HHHHHCCCEEEEEEE		21.7729978859
189PhosphorylationMSNSLEISLISDNEF
HCCCEEEEEEECCCE		15.4129978859
192PhosphorylationSLEISLISDNEFKCR
CEEEEEEECCCEEEE		39.4129978859
201PhosphorylationNEFKCRHSQPECGYG
CCEEEECCCCCCCCC		28.2529978859
207PhosphorylationHSQPECGYGLQPDRW
CCCCCCCCCCCCCCC		26.7329978859
259PhosphorylationVGTACLLSSTIAESG
HHHHHHHCHHHHHCC		16.7025332170
268PhosphorylationTIAESGKSAGILTLP
HHHHCCCCCCEEEEE		34.9425332170
273PhosphorylationGKSAGILTLPIMSRN
CCCCCEEEEEEECCC		28.6825332170
278PhosphorylationILTLPIMSRNSRKTI
EEEEEEECCCCCCCC		29.0927251275
281PhosphorylationLPIMSRNSRKTIGKV
EEEECCCCCCCCCEE		33.7627251275
292PhosphorylationIGKVRVDYIIIKPLP
CCEEEEEEEEEEECC		7.3729759185
301PhosphorylationIIKPLPGYSCDMKSS
EEEECCCCCCCCCCH		12.2729759185
302PhosphorylationIKPLPGYSCDMKSSF
EEECCCCCCCCCCHH		15.0029759185
308PhosphorylationYSCDMKSSFSKYWKP
CCCCCCCHHHHCCCC		28.2024719451
337UbiquitinationTTTAQLAKVQENTIA
CHHHHHHHHHHHHHH		53.71-
424PhosphorylationKSKDRKESVVQEENS
CCCCHHHHHHCCCCC		30.5328857561
431PhosphorylationSVVQEENSFSENQPF
HHHCCCCCCCCCCCC		33.1723312004
497DimethylationVLENSGKRRIVFSSF
HHHHCCCCEEEEEEC		36.76-
498DimethylationLENSGKRRIVFSSFD
HHHCCCCEEEEEECC		32.67-
608PhosphorylationLGVNGLIYDRIYDWM
HCCCCEEHHHHHHHC		12.29-
631AcetylationVEQLERLKQELPELK
HHHHHHHHHHCHHHH		48.2020167786
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GPCP1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GPCP1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GPCP1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of GPCP1_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GPCP1_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory