dbPTM

S35B1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	S35B1_HUMAN
UniProt AC	P78383
Protein Name	Solute carrier family 35 member B1
Gene Name	SLC35B1
Organism	Homo sapiens (Human).
Sequence Length	322
Subcellular Localization	Endoplasmic reticulum membrane Multi-pass membrane protein .
Protein Description	Probable sugar transporter..
Protein Sequence	MASSSSLVPDRLRLPLCFLGVFVCYFYYGILQEKITRGKYGEGAKQETFTFALTLVFIQCVINAVFAKILIQFFDTARVDRTRSWLYAACSISYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKPKKVVGIEEHTVGYGELLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLGMGILFTGELWEFLSFAERYPAIIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPMQWVGTVLVFLGLGLDAKFGKGAKKTSH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	VPDRLRLPLCFLGVF CCCHHHHHHHHHHHH	22.20	-
15 (in isoform 2)	Phosphorylation	-	22.20	22199227
27	Phosphorylation	GVFVCYFYYGILQEK HHHHHHHHHHHHHHH	3.70	27251275
27 (in isoform 2)	Phosphorylation	-	3.70	30266825
29	Phosphorylation	FVCYFYYGILQEKIT HHHHHHHHHHHHHHH	11.62	-
29 (in isoform 2)	Phosphorylation	-	11.62	30266825
33 (in isoform 2)	Phosphorylation	-	42.87	30266825
34 (in isoform 2)	Phosphorylation	-	36.09	30266825
300	Phosphorylation	SPMQWVGTVLVFLGL CHHHHHHHHHHHHCC	10.88	-
337	Phosphorylation	---------------------- ----------------------		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of S35B1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of S35B1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of S35B1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of S35B1_HUMAN

Related Literatures of Post-Translational Modification