S10AA_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: S10AA_MOUSE
• UniProt AC: P08207
• Protein Name: Protein S100-A10
• Gene Name: S100a10
• Organism: Mus musculus (Mouse).
• Sequence Length: 97
• Protein Description: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase..
• Protein Sequence: MPSQMEHAMETMMLTFHRFAGDKDHLTKEDLRVLMEREFPGFLENQKDPLAVDKIMKDLDQCRDGKVGFQSFLSLVAGLTIACNDYFVVNMKQKGKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	QMEHAMETMMLTFHR HHHHHHHHHHHHHHH	8.52	28638064
15	Phosphorylation	AMETMMLTFHRFAGD HHHHHHHHHHHHHCC	10.25	28638064
23	Acetylation	FHRFAGDKDHLTKED HHHHHCCHHHCCHHH	46.24	23806337
28	Acetylation	GDKDHLTKEDLRVLM CCHHHCCHHHHHHHH	56.44	22826441
47	Ubiquitination	PGFLENQKDPLAVDK CCHHHCCCCHHHHHH	73.27	22790023
47	Acetylation	PGFLENQKDPLAVDK CCHHHCCCCHHHHHH	73.27	23236377
54	Acetylation	KDPLAVDKIMKDLDQ CCHHHHHHHHHHHHH	37.79	22826441
54	Ubiquitination	KDPLAVDKIMKDLDQ CCHHHHHHHHHHHHH	37.79	22790023
57	Acetylation	LAVDKIMKDLDQCRD HHHHHHHHHHHHCCC	59.62	22826441
57	Ubiquitination	LAVDKIMKDLDQCRD HHHHHHHHHHHHCCC	59.62	22790023
62	S-nitrosocysteine	IMKDLDQCRDGKVGF HHHHHHHCCCCCCCH	4.23	-
62	Glutathionylation	IMKDLDQCRDGKVGF HHHHHHHCCCCCCCH	4.23	24333276
62	S-nitrosylation	IMKDLDQCRDGKVGF HHHHHHHCCCCCCCH	4.23	21278135
92	Acetylation	DYFVVNMKQKGKK-- CEEEEECHHCCCC--	43.59	15617147

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of S10AA_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of S10AA_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of S10AA_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ANXA2_MOUSE	Anxa2	physical	23415230

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.