RT12_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RT12_HUMAN
• UniProt AC: O15235
• Protein Name: 28S ribosomal protein S12, mitochondrial
• Gene Name: MRPS12
• Organism: Homo sapiens (Human).
• Sequence Length: 138
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MSWSGLLHGLNTSLTCGPALVPRLWATCSMATLNQMHRLGPPKRPPRKLGPTEGRPQLKGVVLCTFTRKPKKPNSANRKCCRVRLSTGREAVCFIPGEGHTLQEHQIVLVEGGRTQDLPGVKLTVVRGKYDCGHVQKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
29	Phosphorylation	PRLWATCSMATLNQM HHHHHHHHHHHHHHH	13.70	-
32	Phosphorylation	WATCSMATLNQMHRL HHHHHHHHHHHHHHH	20.01	-
52	Phosphorylation	PPRKLGPTEGRPQLK CCCCCCCCCCCCCCC	49.64	21406692
122	Ubiquitination	TQDLPGVKLTVVRGK CCCCCCCEEEEEECC	44.34	21890473
129	2-Hydroxyisobutyrylation	KLTVVRGKYDCGHVQ EEEEEECCCCCCCCC	27.61	-
129	Acetylation	KLTVVRGKYDCGHVQ EEEEEECCCCCCCCC	27.61	25825284

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RT12_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RT12_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RT12_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ERG28_HUMAN	C14orf1	physical	16169070
DPYL1_HUMAN	CRMP1	physical	16169070
U119A_HUMAN	UNC119	physical	16169070
LRIF1_HUMAN	LRIF1	physical	16169070

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.