ROGF2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ROGF2_ARATH
• UniProt AC: Q9LQ89
• Protein Name: Rop guanine nucleotide exchange factor 2
• Gene Name: ROPGEF2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 485
• Protein Description: Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP..
• Protein Sequence: MENLPNHEENDDVGYHQSPGPIDPNDHSASETPVYSTMSTDSFAYHRTCSETSGGGFSDQIDETSSFCTEASPSDWPVLTESNNSASSNFPTVFDLKHNQIETDEHLAVQEISEPELETMKERFSKLLLGEDMSGSGKGVCTAVTISNAITNLYATVFGQNLRLEPLEIEQKTTWKREMNCLLSVCDYIFEFIPKSQNLSNGATVEVMESRPRADIYINLPALRKLDSMLMEALDSFQKTEFWYAEEGSLSMKSTRSATGSFRKVIVQRKEEKWWLPIPLVPLQGLSEKARKQLKSKRESTNQIHKAAMAINSSILGEMDIPDSYMATLPKSGKASTGDAIYRHMTSSGRFSPEKLLDRLKIVSEHEALQLADRVEASMYTWRRKACLNNSKSSWNMVKDLMSITERSDKNYVLAERAESLLFCLKQRYPELSQTSLDICKIHCNKDVGKAVLESYSRVLEGLAFNIVAWIDDVLYVDKTMRGEE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
324	Phosphorylation	GEMDIPDSYMATLPK CCCCCCHHHEEECCC	16.08	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ROGF2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ROGF2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ROGF2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RAC5_ARATH	ARAC5	physical	15980860

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.