dbPTM

RNF39_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RNF39_HUMAN
UniProt AC	Q9H2S5
Protein Name	RING finger protein 39
Gene Name	RNF39
Organism	Homo sapiens (Human).
Sequence Length	420
Subcellular Localization	Cytoplasm.
Protein Description	May play a role in prolonged long term-potentiation (LTP) maintenance..
Protein Sequence	MWWRDLTRLRLWLKREAIPGEGRKAAKVNAGVGEKGIYTASSRGGPPSARSKAVTVVAEGAASRSWLSMDAPELGPGLVERLEQLATCPLCGGSFEDPVLLACEHSFCRACLARRWGTPPATGTEASPTACPCCGLPCPRRSLRSNVRLAVEVRISRELREKLAEPGARAGRRRGGRIPTMGCLDLPGEDMRKTWRRFEVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRRLLISADRRSVQLAPPGTPAPPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSSGEDADDEESHYAVGAAGESVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPEPTLLGGVEPPPRRIRVDLDWERGRVAFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
35	Acetylation	VNAGVGEKGIYTASS ECCCCCCCCEECCCC	44.68	11481873
39	Phosphorylation	VGEKGIYTASSRGGP CCCCCEECCCCCCCC	20.38	25003641
41	Phosphorylation	EKGIYTASSRGGPPS CCCEECCCCCCCCCC	16.87	25003641
48	Phosphorylation	SSRGGPPSARSKAVT CCCCCCCCHHCCCEE	39.17	-
51	Phosphorylation	GGPPSARSKAVTVVA CCCCCHHCCCEEEEE	25.36	22210691
55	Phosphorylation	SARSKAVTVVAEGAA CHHCCCEEEEECCHH	17.70	22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RNF39_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RNF39_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RNF39_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
P53_HUMAN	TP53	physical	17719541

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RNF39_HUMAN

Related Literatures of Post-Translational Modification