dbPTM

RMI1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RMI1_SCHPO
UniProt AC	Q10160
Protein Name	RecQ-mediated genome instability protein 1
Gene Name	rmi1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	235
Subcellular Localization	Cytoplasm. Nucleus.
Protein Description	Structure-specific DNA-binding protein with a preference for cruciform structures. Also binds single-stranded DNA (ssDNA). Functions together with top3 to maintain genome integrity. Essential for proper meiotic cell division. Required for normal S-phase progression and DNA damage response..
Protein Sequence	MNQTTTLSTELTELGVRVQNRWLQSLLDYLAKKHSTGANTTPQLVMQYLVASDIRESTTSEGAAPYIVSEQHNVRIENTMLLQIVRVREIGISIVNQLEYLNDLEELKKLKGQKVIRLVHDESGDEEQNDDDGLTEAQDAVQKGSELKKMCRLILEDSNGQRFWGLERKPIKGIQLSTKLGTKLLVKNVLVRRGVLMLDPNNTTILGGSIEEWDKDYFPKRLIEELKGELSKTKA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
123	Phosphorylation	IRLVHDESGDEEQND EEEEECCCCCCCCCC	58.56	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RMI1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RMI1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RMI1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HUS2_SCHPO	rqh1	physical	26771498
YAWC_SCHPO	SPAC3F10.12c	physical	26771498
MDV1_SCHPO	caf4	physical	26771498
DMC1_SCHPO	dmc1	physical	26771498
CBH1_SCHPO	cbh1	physical	26771498
CBH2_SCHPO	cbh2	physical	26771498
YH7G_SCHPO	SPBC16G5.16	physical	26771498
YGNB_SCHPO	nap2	physical	26771498
TAS3_SCHPO	tas3	physical	26771498
YQO1_SCHPO	SPCC569.01c	physical	26771498
MEU23_SCHPO	meu23	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RMI1_SCHPO

Related Literatures of Post-Translational Modification