RLP24_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RLP24_HUMAN
• UniProt AC: Q9UHA3
• Protein Name: Probable ribosome biogenesis protein RLP24
• Gene Name: RSL24D1
• Organism: Homo sapiens (Human).
• Sequence Length: 163
• Subcellular Localization: Nucleus, nucleolus .
• Protein Description: Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity)..
• Protein Sequence: MRIEKCYFCSGPIYPGHGMMFVRNDCKVFRFCKSKCHKNFKKKRNPRKVRWTKAFRKAAGKELTVDNSFEFEKRRNEPIKYQRELWNKTIDAMKRVEEIKQKRQAKFIMNRLKKNKELQKVQDIKEVKQNIHLIRAPLAGKGKQLEEKMVQQLQEDVDMEDAP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Ubiquitination	---MRIEKCYFCSGP ---CCCEEEEEECCC	31.68	-
27	Acetylation	MFVRNDCKVFRFCKS EEEECCCHHHHHHHH	47.47	26051181
27	Ubiquitination	MFVRNDCKVFRFCKS EEEECCCHHHHHHHH	47.47	-
53	Ubiquitination	PRKVRWTKAFRKAAG CHHHHHHHHHHHHCC	38.27	-
61	Acetylation	AFRKAAGKELTVDNS HHHHHCCCCCEECCC	44.84	26051181
61	Ubiquitination	AFRKAAGKELTVDNS HHHHHCCCCCEECCC	44.84	-
64	Phosphorylation	KAAGKELTVDNSFEF HHCCCCCEECCCCCH	27.23	27690223
68	Phosphorylation	KELTVDNSFEFEKRR CCCEECCCCCHHHHC	22.99	21815630
73	Ubiquitination	DNSFEFEKRRNEPIK CCCCCHHHHCCCCCC	63.08	-
80	Ubiquitination	KRRNEPIKYQRELWN HHCCCCCCHHHHHHH	46.15	-
81	Phosphorylation	RRNEPIKYQRELWNK HCCCCCCHHHHHHHH	17.33	-
88	Ubiquitination	YQRELWNKTIDAMKR HHHHHHHHHHHHHHH	34.96	-
88	Acetylation	YQRELWNKTIDAMKR HHHHHHHHHHHHHHH	34.96	26051181
94	2-Hydroxyisobutyrylation	NKTIDAMKRVEEIKQ HHHHHHHHHHHHHHH	55.82	-
94	Ubiquitination	NKTIDAMKRVEEIKQ HHHHHHHHHHHHHHH	55.82	-
100	2-Hydroxyisobutyrylation	MKRVEEIKQKRQAKF HHHHHHHHHHHHHHH	53.71	-
100	Ubiquitination	MKRVEEIKQKRQAKF HHHHHHHHHHHHHHH	53.71	-
106	Ubiquitination	IKQKRQAKFIMNRLK HHHHHHHHHHHHHHH	27.38	21890473
120	Ubiquitination	KKNKELQKVQDIKEV HHCHHHHHHHHHHHH	55.26	-
125	Ubiquitination	LQKVQDIKEVKQNIH HHHHHHHHHHHHHHH	65.82	-
128	Ubiquitination	VQDIKEVKQNIHLIR HHHHHHHHHHHHHHC	38.42	-
128	Sumoylation	VQDIKEVKQNIHLIR HHHHHHHHHHHHHHC	38.42	-
128	Sumoylation	VQDIKEVKQNIHLIR HHHHHHHHHHHHHHC	38.42	-
141	Acetylation	IRAPLAGKGKQLEEK HCCCCCCCCHHHHHH	58.28	26051181
143	Acetylation	APLAGKGKQLEEKMV CCCCCCCHHHHHHHH	56.02	26051181

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RLP24_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RLP24_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RLP24_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FAM9B_HUMAN	FAM9B	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.