dbPTM

RLA2_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RLA2_DROME
UniProt AC	P05389
Protein Name	60S acidic ribosomal protein P2
Gene Name	RpLP2
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	113
Subcellular Localization
Protein Description	Plays an important role in the elongation step of protein synthesis..
Protein Sequence	MRYVAAYLLAVLGGKDSPANSDLEKILSSVGVEVDAERLTKVIKELAGKSIDDLIKEGREKLSSMPVGGGGAVAAADAAPAAAAGGDKKEAKKEEKKEESESEDDDMGFALFE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
41	Acetylation	VDAERLTKVIKELAG CCHHHHHHHHHHHCC	46.70	21791702
44	Acetylation	ERLTKVIKELAGKSI HHHHHHHHHHCCCCH	50.06	21791702
49	Acetylation	VIKELAGKSIDDLIK HHHHHCCCCHHHHHH	38.33	21791702
50	Phosphorylation	IKELAGKSIDDLIKE HHHHCCCCHHHHHHH	30.27	27626673
100	Phosphorylation	KEEKKEESESEDDDM HHHHHHHCCCCCCCC	47.73	21082442
102	Phosphorylation	EKKEESESEDDDMGF HHHHHCCCCCCCCCC	56.45	21082442

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RLA2_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RLA2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RLA2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
ACOX1_DROME	CG5009	physical	14605208
DORS_DROME	dl	physical	14605208

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RLA2_DROME

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of Drosophila melanogaster embryos."; Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.; J. Proteome Res. 7:1675-1682(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-100 AND SER-102, ANDMASS SPECTROMETRY.	18327897 [Abstract]