RL7_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL7_DROME
• UniProt AC: P32100
• Protein Name: 60S ribosomal protein L7
• Gene Name: RpL7
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 252
• Protein Description: Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity)..
• Protein Sequence: MPAPVVKKPAAKKLPAVPESKLKFSKKQISKRVAESKRRLKKAAVIALRKKENLVRAEKYQNEYIKAEQREIKLRRLAKKRNQFYVPAEAKLAFVVRIRGINKVAPKVRKVLQLFRLRQINNGVFIKLNKATINMLRIAEPYITWGYPNLKSVRELIYKRGFVKHNRQRVPITDNFVIERKLRQAHQIQCVEDLVHEIFTVGPNFKYASNFLWPFKLNTPTGGWRKKANHYVNGGDFGNREDQINRLLRKMV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	KLPAVPESKLKFSKK CCCCCCHHHCCCCHH	36.90	22817900
59	Acetylation	ENLVRAEKYQNEYIK HHHHHHHHHHCHHHH	51.67	21791702
66	Acetylation	KYQNEYIKAEQREIK HHHCHHHHHHHHHHH	44.99	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL7_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL7_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL7_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LANC3_DROME	CG2061	physical	14605208
ESM3_DROME	E(spl)m3-HLH	physical	14605208
LIS1_DROME	Lis-1	physical	14605208
MED4_DROME	MED4	physical	14605208

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.